A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
Dale Earnhardt Jr.’s popular No. 88 Chevrolet went “dark” today thanks to fans of The Dark Knight Rises and Mountain Dew® (DEW). Following a week and a half of voting at DEWCrew.com, Earnhardt revealed which “Dark Knight”-inspired paint scheme will be featured on the hood of his No. 88 Chevrolet in Michigan next month. In addition to the Bat Shield on the hood, the redesign features Batman and Bane, Gotham City’s newest villain, on either side of the car. The unveiling continues to drive anticipation for Warner Bros. Pictures’ and Legendary Pictures’ The Dark Knight Rises, before the film’s opening day, July 20.
To view Multimedia News Release, go to http://www.multivu.com/mnr/56313-mtn-dew-dale-earnhardt-jr-no-88-the-dark-knight-rises-paint-scheme
Runner’s World, the authority on running information, will offer comprehensive, real-time coverage and continuous expert analysis of the Olympic Track and Field Trials, which run June 22-July 1 at historic Hayward Field in Eugene, OR.
Runner’s World’s coverage team in Eugene is anchored by longtime Runner’s World editor-at-large Amby Burfoot and veteran Running Times senior editor Scott Douglas, plus award-winning writer John Brant adding occasional columns and commentary, all of which are accessible at www.runnersworld.com/olympic-trials.
To view Multimedia News Release, go to http://www.multivu.com/mnr/56842-runner-s-world-steps-up-july-issue-olympic-track-trials
Landscape Vision is an easy-to-use landscape design software application that produces amazingly professional results because it uses actual plant images! This has got to be the easiest program we have ever used! And it has the biggest plant database available, which includes images and data for each of more than 1000 plants.
Roland Corporation U.S. and Girl Scouts of the USA have announced a Chicago stop on Saturday, May 14 and a New York City stop on May 21st, in conjunction with the national tour of the new Girl Scouts Rock! Initiative, which includes workshops designed to inspire and empower girls through music.
Girl Scouts Rock! Powered by Roland will reach thousands of Girl Scouts and their parents across the country, delivering the message that you can have a “Better Life with Music.” The fun, interactive curriculum co-developed by Roland and Girl Scouts of the USA gets girls pumped up about making music and music education. Girl Scouts Rock! is designed to provide girls ages 8-14 with a hands-on experience playing popular music, an opportunity fewer girls are receiving due to school music budget cuts.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/girlscoutsrock/46002/
Nearly five black women die needlessly per day from breast cancer in the United States – a total of 1,722 deaths annually – according to a study released today at the Avon Foundation Breast Cancer Forum and simultaneously published in Cancer Epidemiology. The 2012 Racial Disparity in Breast Cancer Mortality Study found that 21 of the 25* largest U.S. cities have a black: white disparity in breast cancer mortality, 13 of which are statistically significant.
To view Multimedia News Release, go to http://www.multivu.com/mnr/52895-avon-foundation-breast-cancer-forum-racial-disparity-mortality-study
Computerized tomographic (CT) colonography (CTC), also known as virtual colonoscopy, is comparable to standard colonoscopy in its ability to accurately detect cancer and precancerous polyps in people ages 65 and older, according to a paper published online today in Radiology. This is consistent with results of the ACRIN National CT Colonography Trial, published in the New England Journal of Medicine in 2008, which demonstrated that CT colonography can serve as a primary colorectal cancer screening option for adults ages 50 and older, but did not specifically break out data for participants ages 65 and older included in the overall analysis. The Centers for Medicare and Medicaid Services have deferred coverage for CT colonography, primarily citing a lack of data on the exam’s performance in Medicare-eligible recipients ages 65 and older.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54777-acrin-national-ct-colonography-study-radiology-cancer-screening-seniors
In an unprecedented gesture of love and kindness coinciding with Valentine’s Day on February 14, 2012, the relationship matching services company, Valenti International, announced a pledge today by its Founder, Irene Valenti, to personally donate $5000 along with a commitment to raise an additional $25,000-$30,000 to recoup the losses suffered by the non-profit organization Empty Cradle, which recently fell victim to embezzlement. The fundraising campaign was launched by Valenti International which will collect and administer donations from private individuals, corporations and foundations, plus fund the remainder of the balance until the financial goal is reached.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54440-valenti-international-valentines-day-donation-empty-cradle
Reliance becomes the first private operator in India to showcase 3G services. It chose UTV Bloomberg, which was running a live coverage of the company\\\'s AGM to showcase its ultra fast 3G network and underlying backhaul capablities.
Make Your Childrens to learn algebra with “Hands-On Equations 1 Lite” which brings out the joy of learning in a fun way. Algebra can be a tricky subject to masters but with the help of this app it becomes child\'s play!
The app takes advantage of the iPad’s visual and touch features to demystify complex algebraic concepts.
The app works like this –
The unknown X variable is represented by a blue pawn on the iPad screen while the constants are represented by number cubes.
The game pieces can be moved by the player and placed on a balance scale to represent the two sides of the equation.
The student simplifies the equation by moving the game pieces to solve for the unknown X.
The student resets the problem to conduct the check.
Simple touch features are used to move the pieces around.
An expert instructional video is included
An intuitive user interface makes the app easy to use.
For more details on the app, see the App Store link below.
Download here: http://itunes.apple.com/us/app/fun-way-to-learn-algebra-free/id505954972?mt=8
An Extra-Ordinary Beginning, the debut novel by A.D. Winch about a new kind of superhero, is out now. Children and adults around the world who are tired of the stereotypical superhero – white adult male with his underpants outside his trousers – will find this story is for them.
Ursula and Eric are characters readers can relate to and whose super powers are within their reach. Ursula is originally from Africa and promises to be the first significant superhero for girls regardless of colour, nationality or race. In a genre in which girls are seen as side-kicks or sub-plots, along comes a female character who is central to an entire series of books. This is not to say that the internationally educated Eric is irrelevant. There are more than three million students being educated worldwide who now have a hero who shares their experience and can truly be described as a global citizen.
To view Multimedia News Release, go to http://www.multivu.com/mnr/58648-AD-winch-novel-an-extra-ordinary-beginning
Based on its recent analysis of the Secure Socket Layer (SSL) certificate market, Frost & Sullivan recognizes DigiCert, Inc. with the 2011 North American Frost & Sullivan Award for Customer Value Enhancement. With best-in-class product solutions, competitive pricing and award-winning customer support, DigiCert provides excellent customer value in the market. DigiCert’s Wildcard certificate, for example, is unlike any other in the market, with the ability to secure any subdomain to which the certificate was issued, saving network administrators time and money.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/frostsullivan/54323
