A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
http://www.fudoshinkarate.com More adults are taking up karate and the martial arts than ever before, but many people think karate is a child orientated activity.
This short documentary talks to members of Fudoshin Karate to find out why so many adults are taking up the art.
See more from the club here http://www.fudoshinkarate.com
Today Finnair begins flying direct to Chongqing, one of the largest and fastest-growing cities in China. The new route is a logical next step in the carrier’s strategy of offering the shortest connections between Asia and Europe via Helsinki. Finnair is the first carrier to open a direct flight route between Europe and Chongqing.
Besides booming business activity, Chongqing offers much to see for tourists interested in China’s history and nature. Visitors can enjoy historical buildings, temples, hot springs and natural beauty, as well as the Dazu Rock Carvings, a UNESCO World Heritage Site. Chongqing also provides convenient access to river cruises on the Jialing and Yangtze rivers, and the city is well connected to Lhasa, Xian and Kunming.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/prne/finnair/53815
http://www.modelstopia.com Models Topia, is looking to help undiscovered or new models from around the world get noticed and advance their careers. Our method is very quite simple. We will be searching the web for beautiful models to submit us their videos...to be uploaded on our website along with our new YouTube channel. Your video(s) should be fun, entertaining or informative. Examples: *Modeling shoots. *Interviews. *Day at the beach *Yourself talking on camera. *Playing a sport or activity you enjoy. It can be pretty much anything while looking your best. We want the world to see you!. Unfortunately we can't have any nudity as it restricts the amount of places we can promote your videos, bikinis and lingerie are okay. If your making a new video, we recommend talking a little about yourself...self promotion is always recommended. -No Cost, Our service is 100% free. -We prefer submitted videos in HD. -Absolutely No nudity. We look forward to seeing your video submissions. Models Topia. http://www.modelstopia.com
New research published by Palo Alto Networks™, the network security company, indicates explosive growth in global social networking and browser-based file sharing on corporate networks, with a 300 percent increase in active social networking (e.g., posting, applications) compared with activity during the same period in the latter half of 2010. The Palo Alto Networks Application Usage and Risk Report provides a global view into application usage based on assessments of the raw application traffic from more than 1,600 enterprises between April 2011 and November 2011.
To view Multimedia News Release, go to http://www.multivu.com/mnr/52469-palo-alto-networks-social-networking-applications-growth-research
ChildObesity180 today launched a new initiative, the Active Schools Acceleration Project (ASAP), in the continuing effort toward reversing the trend of childhood obesity. Because of their strong support for Let’s Move!, her initiative to solve the problem of childhood obesity within a generation, First Lady Michelle Obama encouraged participation in the competition with a new video message.
ASAP, in a commitment with The Partnership for a Healthier America (PHA), is conducting a national competition to identify and reward the most creative, impactful, and scalable school-based programs and technological innovations that promote physical activity for children. The contest will award a total of $500,000 in prizes, with individual awards of up to $100,000. In addition to monetary awards, top winners will advance to participate in funded pilot studies aimed at expanding both reach and impact.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54594-childobesity180-innovation-in-physical-activity-competition-for-let-s-move
LeapFrog Enterprises, Inc. (NYSE:LF), the leader in educational entertainment, today announced Tag™ Human Body Discovery Pack, a unique two-sided interactive chart and game board that helps kids learn about the human body through discovery, exploration and play. Today elementary schools do not place enough emphasis on topics of science, healthy habits and nutrition, making it increasingly important to give kids the tools to make smart choices. LeapFrog’s highly experienced team of learning experts partnered with external medical professionals to create and refine the Tag Human Body Discovery Pack. This award-winning tool provides compelling learning experiences as kids learn human body facts, body systems, health and nutrition in a fun and engaging way.
The Tag Human Body Discovery Pack works with the #1 selling Tag™ Reading System and includes a jumbo two-sided chart and game board, interactive growth chart, three interactive sticker sheets with glow-in-the dark bone stickers, and more than 300 interactive responses and 40 learning activities.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54821-leapfrog-tag-human-body-discovery-pack-teach-kids
The duty free and travel retail community assembled last month for the most important event in the industry’s history in the Asia Pacific region. TFWA Asia Pacific & GATE ONE2ONE, the annual conference and exhibition event in Singapore for stakeholders in the industry in the dynamic Asia Pacific region, was larger and better attended than at any time in its 17 year history, evidence of the growth potential of the trade in the dynamic Asia Pacific region.
Revenue from the global duty free and travel retail industry, and other non-aeronautical revenue streams such as advertising, food & beverage and car parking, is of immense importance to airports and to airlines. It not only provides vital funds for the maintenance and development of the airport facilities, its contribution to an airport’s coffers means that airport charges can be held down for airlines and consequently passenger fares can be kept down. It is estimated that 50% of an international airport’s revenue is derived from duty free, travel retail and other non-aviation activity. At Paris Charles de Gaulle airport, for example, commercial activities generate 60% of total revenues for the airport.
To view Multimedia News Release, go to http://www.multivu.com/mnr/53836-tfwa
http://www.blackmagicx.com This video is about black magic and how it can devastate some one\'s life. It explains exact science behind blackmagic a paranormal activity.Please subscribe to my channel. I will upload some interesting videos very soon. Comment if you like the video.
Weather forecasters are predicting a doozy of a hurricane season with above average activity this year. As many as 18 named storms could impact communities along the coast. Hurricanes Sandy, Irene and Isaac serve as sobering reminders of the importance of families being prepared just in case the unthinkable happens. Preparing now, before the weather turns serious, is a family’s best defense.
So where do you start? Preparation should focus on four key activities, which the whole family can do together.
To view the Multimedia News Release, go to http://www.multivu.com/players/English/61576-allstate-be-aware-and-prepare-natural-disaster-weather-alerts
Tree Fu Tom, the animated preschool series that’s taken Britain by storm, will make its U.S. debut on Sprout®, the 24-hour preschool channel, on April 22 at 11:00 a.m. EST. The show, which is a co-production between FremantleMedia Kids & Family Entertainment and CBeebies, joins Sprout’s lineup of quality children’s entertainment that includes both acquired and original programming including the network’s newest hit, “The Chica Show.”
The premiere of Tree Fu Tom kicks-off a week-long celebration called “Dig Into Earth Day,” which promotes conservation and the importance of caring for the environment. Sprout marks Earth Week by being a part of NBCUniversal’s Green is Universal environmental initiative, and will be turning its on-air and online logos green for the entire week.
To view Multimedia News Release, go to http://www.multivu.com/mnr/61203-sprout-animated-preschool-series-tree-fu-tom-makes-u-s-debut-earth-day