A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
Children’s Memorial Hermann Hospital and Cord Blood Registry® (CBR) are launching the first FDA-approved, Phase I safety study on the use of cord blood stem cells to treat children with sensorineural hearing loss.
To view Multimedia News Release, go to http://www.multivu.com/mnr/53686-cord-blood-childrens-memorial-hermann-fda-approved-stem-cells-hearing-loss
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http://debbiewilliamsassociates.co.uk/lean_for_life.htm Healthy fast food using dairy free sauce also curry,chilli and gravy and other sauces to create different dishes everyday to look forward to. Making friends with vegetables will be your greatest ally against disease and helping keeping you slim. Debbie also talks about how you can get raw food into your diet and enjoy it even in the winter. You can see even if you are very lazy (as Debbie admits she is ) there is no excuse to not eat healthy . Adding sprouted seeds to foods after cooking ensures you don\\\'t destroy the enzymes and feed your cells too. This will help with reducing cravings as pointed out autopsies in America ( and other westernised nations) show we are overfed by actually suffering signs of malnutrition. When you live on a diet of highly processed foods the body will send out hunger signals (for many reasons) one of them being an hour or so after eating it realizes there is missing nutrients in this meal, go and get me some please. We interpret this as being hungry and go and eat the first thing we come across and the whole cycle continues. There is a link above to Debbie Williams hypnosis and NLP recording Lean for Life download this and ditch the dairy can help you to break the addiction that many junk foods as well as so called marketed health foods ie \\\'milk and dairy foods have on you. You wouldn\\\'t get down on your hands and knees in a field and suckle of a cow would you? Why not include rat milk or horse milk? One of the reasons we get addicted to dairy is that it contains caso-morphine to ensure the baby has a big desire to drink lots of it. By the time we are 4 years or age most of us lose the ability to fully digest the sugar in milk (lactose) as this is the time we should be fully weaned of our mother\\\'s milk . Drinking milk in adulthood can lead to all sorts of problems one of the best resources for more info is Robert Cohen\\\'s website www.notmilkman.com or my ditch the dairy recording. http://debbiewilliamsassociates.co.uk/ditch_the_dairy.htm
Nearly 90 percent of children and adults with a highly aggressive form of acute lymphoblastic leukemia (ALL) showed no evidence of cancer after receiving a novel, personalized cell therapy that reprograms a patient’s immune system. In pilot studies of bioengineered T cells that attack leukemia, 24 of 27 patients (89%) experienced complete responses within 28 days after treatment. In all, 27 patients received the treatment--22 children treated at The Children’s Hospital of Philadelphia and five adults treated at the Hospital of the University of Pennsylvania.
To view the Multimedia News Release, go to http://www.multivu.com/mnr/64394-chop-penn-harness-engineered-t-cells-eliminate-tumors-in-blood-leukemia
Three and a half years after beginning a clinical trial which demonstrated the first successful and sustained use of genetically engineered T cells to fight leukemia, a research team from the Perelman School of Medicine at the University of Pennsylvania and the Children’s Hospital of Philadelphia will today announce the latest results of studies involving both adults and children with advanced blood cancers that have failed to respond to standard therapies. The findings from the first 59 patients who received this investigational, personalized cellular therapy, known as CTL019, will be presented during the American Society of Hematology’s Annual Meeting and Exposition in New Orleans.
To view Multimedia News Release, go to http://www.multivu.com/mnr/64691-penn-medicine-reports-research-leukemia-patients-cellular-therapy-ctl019
By reprogramming a 7–year–old girl’s own immune cells to attack an aggressive form of childhood leukemia, a pediatric oncologist has achieved a complete response in his patient, who faced grim prospects when she relapsed after conventional treatment. The innovative experimental therapy used bioengineered T cells, custom–designed to multiply rapidly in the patient, and then destroy leukemia cells. After the treatment, the child’s doctors found that she had no evidence of cancer.
To view Multimedia News Release, go to http://www.multivu.com/mnr/50777-chop-engineered-immune-t-cell-therapy-anticancer-effect-in-children
Nestlé Purina, a global leader in the pet care industry, announced today that company scientists have developed new food solutions for middle-aged pets to help sustain a healthier brain as they enter the latter stages of life. The finding is a breakthrough in pet care, providing nourishment to strengthen brain cells to help pets maintain function well into their senior years.
To view the Multimedia News Release, go to http://www.multivu.com/players/English/7236451-nestle-purina-breakthroughs-aging-pets-brain-health/
Spring brings the vibrant colors back to nature and the atmosphere becomes immensely live. It is that time of the year which encourages people to come out of their cozy cells and enjoy the outdoors. Spring is a perfect time to plan vacations and look for destinations that suit their desires.
Janssen-Cilag International NV (Janssen) announced today that the European Commission has approved IMBRUVICA™ (ibrutinib) capsules, a first-in-class, once-daily, oral Bruton’s tyrosine kinase (BTK) inhibitor. This new approach to treating blood cancers works by blocking BTK, a protein that helps certain cancer cells live and grow.1 IMBRUVICA is indicated for the treatment of adult patients with relapsed or refractory mantle cell lymphoma (MCL), or adult patients with chronic lymphocytic leukaemia (CLL) who have received at least one prior therapy, or in first line in the presence of 17p deletion or TP53 mutation in patients unsuitable for chemo-immunotherapy.
To view the Multimedia News Release, go to http://www.multivu.com/players/English/72762540-janssen-ec-approval-imbruvica-mcl-cll/
Alzheimer’s Disease is a disease you might not know a lot about until someone you know has it. It is a progressive disorder where brain cells gradually degenerate and die, causing impairments in memory, learning and mental functioning. In this video you will also learn the 7 stages of Alzheimer’s Disease. http://youtu.be/QCnwJk9lh4g
Today, SunPower launched its Helix™ platform, the world’s first fully-integrated commercial solar solution combining solar power production and energy management.
“Unique in the solar industry, Helix is a complete solution that optimizes power production and maximizes value for our commercial customers, such as Bed Bath and Beyond,” said Tom Werner, president and CEO of SunPower. “Integral to each Helix component, from the solar cells to the energy management system, is SunPower’s 30 years of innovation and experience delivering some of the world’s most efficient, reliable solar technology.”
Helix is a pre-engineered, modular solution that is built to last and fast to install, enabling customers to scale their solar programs quickly with minimal business disruption. The Helix platform is standardized across rooftop, carport and ground installations.
To view the multimedia release go to:
http://www.multivu.com/players/English/7048952-sunpower-helix/
