Researchers have identified the first gene mutation associated with a chronic and often fatal form of neuroblastoma that typically strikes adolescents and young adults. The finding provides the first clue about the genetic basis of the long-recognized but poorly understood link between treatment outcome and age at diagnosis.
The study involved 104 infants, children and young adults with advanced neuroblastoma, a cancer of the sympathetic nervous system. Investigators discovered the ATRX gene was mutated only in patients age 5 and older. The alterations occurred most often in patients age 12 and older. These older patients were also more likely than their younger counterparts to have a chronic form of neuroblastoma and die years after their disease is diagnosed.
To view Multimedia News Release, go to http://www.multivu.com/mnr/52992-st-jude-pediatric-cancer-genome-project-neuroblastoma-research
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Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a much better outcome. The findings from the St. Jude Children’s Research Hospital — Washington University Pediatric Cancer Genome Project (PCGP) highlight a possible new strategy for treating patients with this more aggressive cancer.
The work provides the first details of the genetic alterations fueling a subtype of acute lymphoblastic leukemia (ALL) known as early T-cell precursor ALL (ETP-ALL). The results suggest ETP-ALL has more in common with acute myeloid leukemia (AML) than with other subtypes of ALL. The study appears in the January 12 edition of the journal Nature.
To view Multimedia News Release, go to http://www.multivu.com/mnr/46768-st-jude-cancer-genome-sequencing-project-combat-aggressive-leukemia
The UK\'s biggest marketing and advertising event just got even bigger! TFM&A has consistently achieved impressive growth in visitor numbers since its launch in 2001, and on the 1st and 2nd March, the 2011 edition of the event saw over 12,000* (pending ABC Audit) marketing, media and advertising professionals walk through the doors of Earls Court 2 in just 2 days.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/prne/tfma/48889/
Under the direction of afimilk, the largest, most comprehensive dairy farm project in the world has entered its third year, and is operating in five of 12 farms with 23,000 cattle. The project, located in Vietnam, was planned and constructed by on-site afimilk experts.
To view Multimedia News Release, go to http://www.multivu.com/mnr/58628-afimilk-largest-dairy-farm-project
Miramar Labs today announced that the miraDry System for the treatment of primary axillary hyperhidrosis, commonly known as excessive underarm sweat, is now available to select physicians in the U.S. The miraDry procedure provides a safe and lasting solution for this debilitating condition.
The U.S. Food & Drug Administration granted clearance for miraDry following a robust, randomized, blinded clinical study that involved 120 patients at seven clinics and followed them 12-months post treatment. The miraDry System delivers energy non-invasively to the area under the arm where the sweat glands reside which creates localized heat to destroy and eliminate the glands. Since sweat glands do not regenerate, results are lasting.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54021-miramar-labs-miradry-treat-excessive-underarm-sweat-axillary-hyperhidrosis
Sanofi (EURONEXT: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that data from two Phase 2 trials with SAR236553/REGN727, an investigational, high-affinity, subcutaneously administered, fully-human antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9), were presented at the American College of Cardiology’s (ACC) 61st Annual Scientific Meeting in Chicago.
The data showed that treatment with SAR236553/REGN727 over 8 to 12 weeks significantly reduced mean low-density lipoprotein-cholesterol (LDL-C, or “bad” cholesterol) by 40% to 72% in patients with elevated LDL-C on stable dose of statins.
To view Multimedia News Release, go to http://www.multivu.com/mnr/55299-sanofi-regeneron-pharmaceuticals-lipid-lowering-medications-pcsk9-antibody
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Sydney Fialkow, 10, and her mother Stacy, 41, of Atlanta were named the grand prize winners of the Ben’s Beginners™ Cooking Contest. The playful nationwide competition, sponsored by the UNCLE BEN’S® Brand, the number-one selling brand of rice in the United States, was designed to empower and encourage parents to connect with their kids one meal at a time.
Sydney Fialkow was selected from a field of more than 700 contestants (ages 5-12) who videotaped themselves preparing a kid-friendly rice dish and discussing the experience of cooking with their parents. The contestants were narrowed to four finalists, from which the Fialkows were selected as the grand prize winners. The Fialkow family has won a $20,000 cash prize and a $50,000 cafeteria makeover for The Epstein School, located in Sandy Springs, Ga., where Sydney attends as a fourth grade student.
To view Multimedia News Release, go to http://www.multivu.com/mnr/55947-uncle-ben-s-awards-cash-prize-in-ben-s-beginners-cooking-contest
CGAP recently conducted a study of 426 Mexican households with income below $1,440 per month in an effort to better understand the financial habits, needs and wants of low-income customers. The nationally representative survey helped segment customers into six groups with common needs and behavior towards financial services. The study highlights in particular four lower-income groups – those living on US$4-10 per day (seasonal workers), US$10 per day (entrepreneurs), US$15 per day (informal salaried/wage workers) and US$12 per day (formal salaried workers) – and found that even across these income segments, households’ financial concerns and aspirations were similar.
To view Multimedia News Release, go to http://www.multivu.com/mnr/50762-cgap-analysis-low-income-households-in-mexico-matches-financial-products
