A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
zNitro (znitro.com), a Clear Protector company, today announced it will launch its exclusive lineup of Nitro electronics accessories at the Macworld/iWorld Show 2013. zNitro will be located at Booth 809 in the Moscone Center of this gala San Francisco event scheduled for January 31- February 2, 2013.
Building on the exceptional reputation for quality established by its Clear Protector predecessor, zNitro will continue to offer outstanding value and top-of-the-line products for consumers.
To view Multimedia News Release, go to http://www.multivu.com/mnr/59895-former-clear-protector-znitro-mobile-electronic-devices-accessories
(Casha)
If you know exactly what I wanna do
Then I'm a give the business to you
[Verse 1:]
See I ain't neva met a girl
That's getting down like you
(never met a girl like you baby)
And I ain't neva met a girl
That put it down like you
(you know you make it do what it do baby)
(Ay ay ay)
Say thug in yo life
That's what you need shawty
Anything you want
It's guarenteed for my
Boo boo boo boo boo
yea yea yea
And I ain't tryina go hard
For what I need shawty
I'm tryina tell you exactly what I need from
You you you you you
Cause you know I wanna
[Chorus:]
A Freak in morning
A Freak in the evening
Just call me up and I'll be there when you need me
When ever you want me you can come and see me
Cause you know just what to do
You give me the business
Give me the business
Give me the business
You give me the business
Shawty give me the business
If you know exactly what I wanna do (You want it too)
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
(Can I give you the business shawty)
(Can I give you the business shawty)
(From the show to the afterparty)
Baby I'm a give the business to you
[Verse 2:]
Ay,that business baby
Cause I really wanna drive you crazy
Wanna kiss wanna rub wanna lick wanna touch
Wanna put it inside you baby
Wanna climb on top of you
And give it to you for a hour or two
until you cum I
Wannna hit it from the back
Ooo stroke, stroke for a minute or two
Because ya so tight
Booty hung right
Got her tongue right
Ride with me
To the sunlight
We can have a little Sex in the City baby
You can be Carrie
I'm a be Mr. Biggs
Cause you so fine
And you just right
But you look much better with me
So let me manage ya girl
And did I eva tell ya
That it's nice to know ya
And you know I wanna
[Chorus:]
A Freak in morning
A Freak in the evening
Just call me up and I'll be there when you need me
When ever you want me you can come and see me
Cause you know just what to do
You give me the business
Give me the business
Give me the business
You give me the business
Shawty give me the business
If you know exactly what I wanna do (You want it too)
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
(Can I give you the business shawty)
(Can I give you the business shawty)
(From the show to the afterparty)
Baby I'm a give the business to you
[Bridge:]
Lets talk about that business baby
It's more than just a 8 letter word
It describes me and you
And what we do
Hold on this shit is so good, I gotta repeat fa ha
Ya, see you been playing all night
Now its time to handle business baby
Keep goin hard on ya job when ya do it
Ma, you drive me crazy
You drivin me crazy when ya
Give me the business
G-give me give me, g-give me give me, give me the business
G-give me the business
Shawty give me the business
If, if, if, if you know exactly what I wanna do
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
(Can I give you the business shawty)
(Can I give you the business shawty)
(From the show to the afterparty)
Baby I'm a give the business to you
French attorney Christophe Jensen turns African American Tia Edwards’ life upside down. She is happier than she’s ever been, but complications arise when Christophe is summoned back to France. Suddenly, the best time of Tia’s life starts falling apart, as she’s forced to choose between her family or her future with a man whose home is in another country. Learn more about this book: http://bit.ly/9ImVi1 Learn more about this author: http://www.karenwhiteowens.com
Australians are closely linked to the sea through commerce, defence, exploration, adventure, sport and play. Our oceans and waterways have influenced our development...and who we are.
The museum captures these themes with fascinating artefact\\\\\\\'s, lively exhibitions, fun activities and even the chance to board ships and experience life on the water.
This summer, experience AQUA: A Journey into the World of Water, a multisensory experience for the whole family. created by ONE DROP, an initiative of Guy Lailberté, Founder of Cirque du Soleil®. http://www.onedrop.org/en/default.aspx
Only in Australia at the Australian National Maritime Museum, Darling Harbour Sydney from 3 December 2011 - 26 February 2012.
http://www.anmm.gov.au/aqua
This summer, join us on Facebook for the chance to WIN great prizes.
http://www.facebook.com/anmmuseum
YouTube Statistics 2013 | http://JessicaBrace.com
As one of the fastest growing social sites the statistics on YouTube are staggering. This short video will show you the data you need to know to make an informed decision on which social media platform is best for you.
Please share this video: http://www.youtube.com/watch?v=wK1NMnZG_K4
YouTube is growing SO fast! Did you know that over 20 HOURS of video are uploaded to youtube per minute? It begs the question... Do you have a YouTube Marketing Strategy? http://www.youtube.com/watch?v=4AgSQpsV_1w
World Water Day is March 22, and the children and youth of Children International are celebrating around the world. They know firsthand the difference clean, accessible water can make in their lives.
Some of them also know what it feels like to make clean water available to others. In 2012, the youth of Children International in Lusaka, Zambia, dedicated their Youth Empowerment Fund to extend the supply of clean, piped water to the poor community of Chibolya.
To view Multimedia News Release, go to http://www.multivu.com/mnr/57995-children-international-world-water-day
Walden University Scholars of Change focus on the future, whether they are transforming the way children learn, mentoring, or improving living conditions for others. More than 175 Walden University students and alumni submitted inspiring videos of social change in their communities for the university’s 2014 Scholars of Change video contest. These scholars–along with hundreds of their fellow video contributors–are supporting Walden’s mission by putting their knowledge to use for the greater good.
To view the Multimedia News Release, go to: http://www.multivu.com/players/English/7388451-walden-university-scholars-of-change/
Children International’s 2013 Youth Report is available beginning today, International Youth Day. The report explains how Children International’s youth programs, with community centers at the core, measurably change outcomes for impoverished youth. The majority of the world’s 1.7 billion young people ages 10 to 24 live in developing countries – many in extreme poverty where they routinely confront threats to their personal safety and progress. Without positive intervention like Children International’s successful youth programs, these at-risk youth can remain trapped in an intergenerational cycle of poverty.
To view the Multimedia News Release, go to http://www.multivu.com/mnr/57997-children-international-2013-youth-report-results-now-available
During a round of Truth or Dare, Abby Miller confesses her crush on Jake Chilson to her friends. That night, she gets a creepy text message warning her to stay away from Jake. It may have been sent by a jealous classmate or, as Abby begins to suspect, a ghost. Learn more about this and the other You’re Invited to a Creepover books here, www.CreepoverBooks.com Tween girls, ages 8-12
A North Korean spy, heavily undercover and long dormant in the South, is suddenly called back to headquarters. Spanning the course of one day, Your Republic is Calling You explores how a secret divides a family and the long and insidious effects of dividing a nation in two. Learn more about the book: http://bit.ly/clA8qv Fiction / Psychological Thriller
