A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
(Casha)
If you know exactly what I wanna do
Then I'm a give the business to you
[Verse 1:]
See I ain't neva met a girl
That's getting down like you
(never met a girl like you baby)
And I ain't neva met a girl
That put it down like you
(you know you make it do what it do baby)
(Ay ay ay)
Say thug in yo life
That's what you need shawty
Anything you want
It's guarenteed for my
Boo boo boo boo boo
yea yea yea
And I ain't tryina go hard
For what I need shawty
I'm tryina tell you exactly what I need from
You you you you you
Cause you know I wanna
[Chorus:]
A Freak in morning
A Freak in the evening
Just call me up and I'll be there when you need me
When ever you want me you can come and see me
Cause you know just what to do
You give me the business
Give me the business
Give me the business
You give me the business
Shawty give me the business
If you know exactly what I wanna do (You want it too)
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
(Can I give you the business shawty)
(Can I give you the business shawty)
(From the show to the afterparty)
Baby I'm a give the business to you
[Verse 2:]
Ay,that business baby
Cause I really wanna drive you crazy
Wanna kiss wanna rub wanna lick wanna touch
Wanna put it inside you baby
Wanna climb on top of you
And give it to you for a hour or two
until you cum I
Wannna hit it from the back
Ooo stroke, stroke for a minute or two
Because ya so tight
Booty hung right
Got her tongue right
Ride with me
To the sunlight
We can have a little Sex in the City baby
You can be Carrie
I'm a be Mr. Biggs
Cause you so fine
And you just right
But you look much better with me
So let me manage ya girl
And did I eva tell ya
That it's nice to know ya
And you know I wanna
[Chorus:]
A Freak in morning
A Freak in the evening
Just call me up and I'll be there when you need me
When ever you want me you can come and see me
Cause you know just what to do
You give me the business
Give me the business
Give me the business
You give me the business
Shawty give me the business
If you know exactly what I wanna do (You want it too)
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
(Can I give you the business shawty)
(Can I give you the business shawty)
(From the show to the afterparty)
Baby I'm a give the business to you
[Bridge:]
Lets talk about that business baby
It's more than just a 8 letter word
It describes me and you
And what we do
Hold on this shit is so good, I gotta repeat fa ha
Ya, see you been playing all night
Now its time to handle business baby
Keep goin hard on ya job when ya do it
Ma, you drive me crazy
You drivin me crazy when ya
Give me the business
G-give me give me, g-give me give me, give me the business
G-give me the business
Shawty give me the business
If, if, if, if you know exactly what I wanna do
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
Then I'm a give the business to you
Oh, oh ohohoh, oh oh ohohoh
(Can I give you the business shawty)
(Can I give you the business shawty)
(From the show to the afterparty)
Baby I'm a give the business to you
Australians are closely linked to the sea through commerce, defence, exploration, adventure, sport and play. Our oceans and waterways have influenced our development...and who we are.
The museum captures these themes with fascinating artefact\\\\\\\'s, lively exhibitions, fun activities and even the chance to board ships and experience life on the water.
This summer, experience AQUA: A Journey into the World of Water, a multisensory experience for the whole family. created by ONE DROP, an initiative of Guy Lailberté, Founder of Cirque du Soleil®. http://www.onedrop.org/en/default.aspx
Only in Australia at the Australian National Maritime Museum, Darling Harbour Sydney from 3 December 2011 - 26 February 2012.
http://www.anmm.gov.au/aqua
This summer, join us on Facebook for the chance to WIN great prizes.
http://www.facebook.com/anmmuseum
During a round of Truth or Dare, Abby Miller confesses her crush on Jake Chilson to her friends. That night, she gets a creepy text message warning her to stay away from Jake. It may have been sent by a jealous classmate or, as Abby begins to suspect, a ghost. Learn more about this and the other You’re Invited to a Creepover books here, www.CreepoverBooks.com Tween girls, ages 8-12
LG and entertainment’s A-list celebrated old and new Hollywood glamour last night at the 14th Annual Young Hollywood Awards presented by Bing. Held at the historic Hollywood Athletic Club, LG Mobile sponsored the exclusive event to honor the accomplishments of Tinseltown’s up-and-coming film and TV stars.
Getting the scoop from celebrity attendees, LG Girl Stephanie Duchaine helped some of Hollywood’s finest keep their fans up-to-speed on the night’s events using the stylish LG Optimus Elite. Slim, fast and eco-friendly, LG Optimus Elite makes staying in touch while on-the-go easier than ever by offering an integrated Android, Google and social networking smartphone experience. With LG Girl’s help, guests were able to tweet and capture photos directly from the red carpet as well as the Young Hollywood Awards Pre-Cocktail Party Sponsored by LG.
To view Multimedia News Release, go to http://www.multivu.com/mnr/56682-lg-sponsors-young-hollywood-awards
Nine West, the go-to destination for fashionistas, has teamed up with Kelly Cutrone, newly appointed brand Ambassador of Culture and Noise, CEO and Founder of public relations firm People’s Revolution, New York Times Best Selling author, judge on America’s Next Top Model and widely recognized TV personality, and Elizabeth Arden Red Door Spa to support young women through the power of transformation.
Taking into consideration the current economic environment and using the formidable social media platform of Facebook, Nine West created the You’ve Been Prom’d program as a way to give back to the community and offer one lucky high school a prom experience of a lifetime. Contestants entered to win a full prom makeover from Kelly Cutrone with some surprises along the way.
To view Multimedia News Release, go to http://www.multivu.com/mnr/56326-nine-west-kelly-cutrone-elizabeth-arden-red-door-spa-prom-makeover-hs-girl
This toothbrush rap music or call it hip hop music from http://ToothBrushIt.com is very nice. It advises people to regularly brush their teeth and to buy their toothbrush from ToothBrushIt.com website, in a hillarious way. Check it out!!!
The topic of friends is in many times overlooked or underrated whether the talk is about having good friends or staying away from the bad ones. This video is filled with evidences from the Quran, Sunnah and real life examples of how friends influence you in this life, in the grave and in the afterlife. This topic should be learnt by every Muslim. May Allah bless you and gathering you on the day of judgment with Prophet Muhammad -salla Allahu alayhe wa sallam-.
The topic of friends is in many times overlooked or underrated whether the talk is about having good friends or staying away from the bad ones. This video is filled with evidences from the Quran, Sunnah and real life examples of how friends influence you in this life, in the grave and in the afterlife. This topic should be learnt by every Muslim. May Allah bless you and gathering you on the day of judgment with Prophet Muhammad -salla Allahu alayhe wa sallam-.
The topic of friends is in many times overlooked or underrated whether the talk is about having good friends or staying away from the bad ones. This video is filled with evidences from the Quran, Sunnah and real life examples of how friends influence you in this life, in the grave and in the afterlife. This topic should be learnt by every Muslim. May Allah bless you and gathering you on the day of judgment with Prophet Muhammad -salla Allahu alayhe wa sallam-.
The topic of friends is in many times overlooked or underrated whether the talk is about having good friends or staying away from the bad ones. This video is filled with evidences from the Quran, Sunnah and real life examples of how friends influence you in this life, in the grave and in the afterlife. This topic should be learnt by every Muslim. May Allah bless you and gathering you on the day of judgment with Prophet Muhammad -salla Allahu alayhe wa sallam-.
The topic of friends is in many times overlooked or underrated whether the talk is about having good friends or staying away from the bad ones. This video is filled with evidences from the Quran, Sunnah and real life examples of how friends influence you in this life, in the grave and in the afterlife. This topic should be learnt by every Muslim. May Allah bless you and gathering you on the day of judgment with Prophet Muhammad -salla Allahu alayhe wa sallam-.
