New findings from the St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project (PCGP) have helped identify the mechanism that makes the childhood eye tumor retinoblastoma so aggressive. The discovery explains why the tumor develops so rapidly while other cancers can take years or even decades to form.
The finding also led investigators to a new treatment target and possible therapy for the rare childhood tumor of the retina, the light-sensing tissue at the back of the eye. The study appears in the January 11 advance online edition of the scientific journal Nature.
To view Multimedia News Release, go to http://www.multivu.com/mnr/46767-st-jude-genome-project-treatment-childhood-eye-tumor-retinoblastoma
Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a much better outcome. The findings from the St. Jude Children’s Research Hospital — Washington University Pediatric Cancer Genome Project (PCGP) highlight a possible new strategy for treating patients with this more aggressive cancer.
The work provides the first details of the genetic alterations fueling a subtype of acute lymphoblastic leukemia (ALL) known as early T-cell precursor ALL (ETP-ALL). The results suggest ETP-ALL has more in common with acute myeloid leukemia (AML) than with other subtypes of ALL. The study appears in the January 12 edition of the journal Nature.
To view Multimedia News Release, go to http://www.multivu.com/mnr/46768-st-jude-cancer-genome-sequencing-project-combat-aggressive-leukemia
Adolescents and young adults with a severe inherited immunodeficiency disorder improved following treatment with novel gene therapy developed at St. Jude Children’s Research Hospital and at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The results of this study appear today in the journal Science Translational Medicine.
The study involved five males with X-linked severe combined immunodeficiency disease (SCID-X1), also known as “Bubble Boy” disease, who were all treated at NIAID. This inherited disorder involves a mutation in the IL2RG gene that affects males and occurs in 1 of every 50,000 to 100,000 live births, leaving them with little to no immune protection.
To view the multimedia release go to:
http://www.multivu.com/players/English/7808651-st-jude-gene-therapy-results/
Symptoms improved significantly in adults with the bleeding disorder hemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children’s Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the U.K.
The findings of the six-person study mark the first proof that gene therapy can reduce disabling, painful bleeding episodes in patients with the inherited blood disorder. Results of the Phase I study appear in the December 10 online edition of the New England Journal of Medicine. The research is also scheduled to be presented December 11 at the 53rd annual meeting of the American Society of Hematology in San Diego.
To view Multimedia News Release, go to http://www.multivu.com/mnr/46766-st-jude-children-s-research-hospital-gene-therapy-bleeding-disorder
Mr. Freeze: Reverse Blast was introduced at Six Flags St. Louis today with St. Louis Cardinal and World Series MVP David Freese on-hand for the first official ride. Eighteen members of Big Brothers Big Sisters of St. Louis joined Freese for the inaugural launch-ride on the park’s newest twist to one of its most popular thrill rides. Mr. Freeze: Reverse Blast sends riders backwards through a 190-foot tunnel, into a 180-degree inversion, then climbs more than 200-feet in the air where they will find themselves suspended, dangling in the air, before repeating the entire chilling experience.
“I have been coming to Six Flags since I was a kid and the roller coasters have always been my favorite,” said Freese. “I was really excited to ride Mr. Freeze: Reverse Blast. The backwards launch and experience of going up the tower facing straight down is a real rush.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/55951-mr-freeze-reverse-blast-launches-at-six-flags-st-louis
Scott proposed to Betty Torrie last night. And he said YES. He has made her the happiest woman in the world. They are so so so in love. Thier marraige will be on the 3rd August at St Magarets Church in Fofar. And everyone is so so so welcome.
She is so happy, and they are going to have loads of babies.
No bucket list is complete without spending a St Patrick’s Day in Ireland. Our patron saint left a legacy that stretches from one end of the island to the other.
The ‘Home of St Patrick’ festival in Northern Ireland is set around Downpatrick and Armagh where St Patrick lived and where he is buried. This 10 day festival will celebrate the achievements of Patrick, the man, with a spectacular themed program across the region.
The single biggest event on the island is the St Patrick’s Festival in Dublin. It is truly one of the great spectacles of the world — a week-long celebration of music, dance and outdoor shows culminating in the stunning St. Patrick’s Day parade through the historic streets of Dublin on March 17th.
To view the multimedia release go to:
https://www.multivu.com/players/English/8274051-ireland-st-patricks-day-globalgreening/
http://exodraft.de/uncategorized/mit-dem-kaminofen-loslegen-ohne-rauchpartikel/
Rauchpartikel vom Kaminofen lösten Allergiebeschwerden aus und machte es nahezu unmöglich für die Familie Damsted ihren hochwertigen Ofen zu benutzen. Sehen Sie im Film, wie das Problem durch den Einsatz von einem Rauchsauger gelöst wurde.
Kumsaldaki bi kum taneciğinin üstünde yaşayan mikroorganizmadan farksız olan insan nasıl herşeyin merkezi olduğu ve herşeyin insana hizmet etmek için varolduğu küstahlığına kapılabilir?
Kaynak:
http://www.facebook.com/pages/Beyindeki-Süpernova
http://www.facebook.com/karikateist
