A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
Maxine Carter is the best bonded courier working in the Pacific Rim. But her next task involves delivering a bratty 15-year old named Alice to her mother in the U.S. amid a bitter custody battle. Little does Maxine know that a trap is waiting for them, and its up to her to keep Alice safe, providing they dont kill each other first. Premieres December 21st at 8pm ET on Lifetime Movie Network!
Meet Karma. new episode each week on http://www.comediva.com/ http://anniewood.com/ https://twitter.com/anniewood https://www.facebook.com/welcometoanniewood http://pinterest.com/gypsywood/ http://www.lizbenham.com http://www.ericjcurtis.com http://www.roundaboutpictures.com cast:
Annie Wood, Eric Curtis, Liz Benham, Cameron Diskin, Peter Arpesella,
Matthew J Cates, Stephanie Erb, Phillip Estrada, Teresa Ganzel, Susie
Geiser, Jill K. Allen, Arthur Hanket, Hali Lula Hudson, Bill
Lippincott, DeLane Matthews, Erin Murphy, Brian Prisco, Mikul Robins,
Leif Ronalds, Rachel Sciacca, Chelsea Switzer crew: Kyle
Stryker, Zach Voytas, Alex Pulido, Ryan Villarreal, Brian Ronalds, Chad
Villella, Ryan Hetrick, Josh Benham & Jon LaFleur - The Crafty
Caterer! http://www.craftycaterer.com/
Charles Barkley says that high school basketball players should have to spend two years in college before being drafted. Do the fans agree? Find out on FANARCY, Tuesdays at 10:30ET on VERSUS.
