A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
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BioPharmX Corporation (OTCQB: BPMX) today announced the availability of Violet™ iodine, a new, once-daily pill for relief of premenstrual breast discomfort. The first-of-its-kind product is based on the latest molecular iodine technology designed to help free women from the burden of breast discomfort by addressing the underlying causes of a condition known as fibrocystic breast condition (FBC), with the added benefit of promoting breast health for women of reproductive age.*
*These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
To view the Multimedia News Release, go to http://www.multivu.com/players/English/7378951-biopharmx-introducing-violet-iodine-premenstrual-breast-discomfort/
If you don’t sleep well, then you need to take a natural sleeping pill. Melatonin is one of the least expensive ways to take care of this problem. The nice thing about melatonin supplements is that it is not only good for producing sound sleep it also provides your body with the melatonin it needs.
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Two Merck research scientists, Nancy A. Thornberry and Ann E. Weber, Ph.D., will receive the Discoverers Award, the highest honor from the Pharmaceutical Research and Manufacturers of America (PhRMA), during a ceremony tonight at the Liberty Science Center in Jersey City, N.J.
They will be recognized for their leadership in the discovery of JANUVIA®, a once-daily pill that helps patients with type 2 diabetes control glucose in conjunction with diet and exercise. Though women have been part of teams honored with the Discoverers Award in the past, this is the first time in the award’s 24-year history that women alone have won.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/phrma/49723/
