A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
In an effort to continue to create and place people in more jobs, including people who are unemployed or underemployed, Goodwill® and the Ad Council have launched new public service advertisements (PSAs) that demonstrate how donated clothing and household items to Goodwill support those facing challenges to finding employment. Every 27 seconds of every business day, Goodwill helps someone find employment.
To view the Multimedia News Release, go to: http://www.multivu.com/players/English/7442751-goodwill-ad-council-psas/
Random letters which come floating down a waterfall need to be connected to form words before time runs out. The face of each letter tile shows a value from 1 to 10, based on which your score is decided. Every word spelled correctly earns you points. The more letters you string together, the bigger your score gets! If you aren\\\'t quick enough to grab the letters you need as they move down the screen, they just get washed away!
Robert ‘Reb’ Rose and Ashlee met in high school and knew they were destined to be together. After many years of marriage, three daughters and a bright future ahead of them, the unthinkable happened and Reb didn’t make it home.
This is the story of how Ashlee and her daughters were able to move forward in the aftermath of a tragedy.
To view Multimedia News Release, go to http://www.multivu.com/mnr/59530-northwestern-mutual-client-story-a-world-without-reb
Expanding the functionality of Internet of Things (IoT) networks, Texas Instruments (TI) (NASDAQ: TXN) today announced availability for mass production of the industry’s lowest-power dual-band wireless microcontroller (MCU) supporting Sub-1 GHz and Bluetooth® low energy connectivity on a single chip. As part of TI’s pin-to-pin and software compatible SimpleLink™ ultra-low power platform, the new SimpleLink dual-band CC1350 wireless MCU enables developers to move from a three-chip solution to a tiny single chip, while reducing design complexity, saving power, cost and board space. The CC1350 wireless MCU offers a range of up to 20 km on a coin cell battery for building and factory automation, alarm and security, smart grid, asset tracking and wireless sensor network applications. For more information, visit www.ti.com/cc1350-pr.
To view the multimedia release go to:
http://www.multivu.com/players/English/7746254-texas-instruments-simplelink-dual-band-cc1350/
Beginning this Earth Day (April 22), Whole Foods Market (NASDAQ: WFM) will no longer carry red-rated, wild-caught fish in its seafood departments. The move, which comes one year ahead of the company’s self-imposed deadline of Earth Day 2013, makes Whole Foods Market the first national grocer to stop selling red-rated seafood.
A red rating indicates that a species is suffering from overfishing or that current fishing methods harm other marine life or habitats; the ratings are determined by nonprofit research organizations Blue Ocean Institute and Monterey Bay Aquarium.
Blue Ocean Institute and Monterey Bay Aquarium’s green or “Best Choice” ratings mean species are abundant and are caught in environmentally friendly ways; yellow or “Good Alternative” ratings indicate some concerns with the species’ status or catch methods.
To view Multimedia News Release, go to http://www.multivu.com/mnr/49713-sustainable-seafood-whole-foods-eliminates-red-rated-wild-caught-fish
For the first time in the 80-year history of the brand, Wheaties will offer America the opportunity to select the next elite athlete to be featured nationally on the iconic Wheaties box. Kicking off today is the Wheaties NEXT Challenge powered by the leader in Connected Fitness, MapMyFitness. Five world-class athletes from five emerging sports will compete for this honor in an innovative way—by asking their fans to get out and move. Challenge participants will vote for their favorite athlete by logging workouts through the MapMyFitness platform – either manually documenting online, recording through any of the apps (MapMyFitness, MapMyRun, MapMyRide, MapMyWalk) or by connecting any one of the 400+ compatible devices. The Wheaties NEXT Challenge runs through August 31, and the athlete with the most votes via workouts logged will appear on the Wheaties box in early 2015.
To view the Multimedia News Release, go to http://www.multivu.com/players/English/7260151-wheaties-fans-to-elect-america-s-next-box-champion/
The North American International Auto Show (NAIAS) today revealed new programs and major improvements that will make the entire show experience more convenient, and more productive for both media and auto manufacturers.
To assist journalists covering the show, the Michelin Media Center will move from the third level of Cobo Center to Michigan Hall (river level). And, to ease travel to Detroit for both media and manufacturer personnel, Delta Air Lines is offering a discount airfare program, along with travel assistance from Passageways Travel.
To view Multimedia News Release, go to http://www.multivu.com/mnr/59256-north-american-international-auto-show-naias-new-programs-improvements
New entertainment integrations and social media initiatives move the “ugly truth” campaign into a new phase this month, further seeding important tobacco-related facts and messages with teens and young adults. The latest advertising campaign from truth – the nation’s largest youth smoking prevention campaign – features its first television ads since 2010, and a host of marketing and digital tools to educate and connect with teens and young people through a range of digital media initiatives and entertainment integrations.
To view Multimedia News Release, go to http://www.multivu.com/mnr/62254-truth-campaign-gets-uglier-entertainment-integrations-expand-conversation
Admittedly, there’s a risk in any course we follow other than this, but every lesson of history tells us that the greater risk lies in appeasement, and this is the specter our well-meaning liberal friends refuse to face—that their policy of accommodation is appeasement, and it gives no choice between peace and war, only between fight or surrender. If we continue to accommodate, continue to back and retreat, eventually we have to face the final demand—the ultimatum. And what then—when Nikita Khrushchev has told his people he knows what our answer will be? He has told them that we’re retreating under the pressure of the Cold War, and someday when the time comes to deliver the final ultimatum, our surrender will be voluntary, because by that time we will have been weakened from within spiritually, morally, and economically. He believes this because from our side he’s heard voices pleading for “peace at any price” or “better Red than dead,” or as one commentator put it, he’d rather “live on his knees than die on his feet.” And therein lies the road to war, because those voices don’t speak for the rest of us.
You and I know and do not believe that life is so dear and peace so sweet as to be purchased at the price of chains and slavery. If nothing in life is worth dying for, when did this begin—just in the face of this enemy? Or should Moses have told the children of Israel to live in slavery under the pharaohs? Should Christ have refused the cross? Should the patriots at Concord Bridge have thrown down their guns and refused to fire the shot heard ’round the world? The martyrs of history were not fools, and our honored dead who gave their lives to stop the advance of the Nazis didn’t die in vain. Where, then, is the road to peace? Well it’s a simple answer after all.
You and I have the courage to say to our enemies, “There is a price we will not pay.” “There is a point beyond which they must not advance.” Winston Churchill said, “The destiny of man is not measured by material computations. When great forces are on the move in the world, we learn we’re spirits—not animals.” And he said, “There’s something going on in time and space, and beyond time and space, which, whether we like it or not, spells duty.”
You and I have a rendezvous with destiny.
We’ll preserve for our children this, the last best hope of man on earth, or we’ll sentence them to take the last step into a thousand years of darkness.”
For decades, drivers have been accustomed to accessing and driving cars with physical keys. But no longer. In a ground-breaking move for the automotive industry, Volvo Cars plans to become the world’s first car manufacturer to offer cars without keys from 2017.
Volvo customers will be offered an application for their mobile phones to replace the physical key with a digital key. The innovative Bluetooth-enabled digital key technology, will offer Volvo customers far more flexibility, enabling them to benefit from entirely new ways to use and share cars.
The new Volvo app enables the digital key on the customer’s mobile phone to do everything a physical key currently does, such as locking or unlocking the doors or the boot and allowing the engine to be started.
This new technology will also offer customers the possibility to receive more than one digital key on their app allowing them to access different Volvo cars in different locations – according to their changing mobility needs.
To view the multimedia release go to:
http://www.multivu.com/players/uk/7761852-volvo-phone-as-key/
In a ground-breaking technology move for the automotive industry, Volvo Cars demonstrates the world’s first delivery of food to the car – a new form of ‘roam delivery’ services. The service, which will be showcased at the Mobile World Congress, will allow consumers to have their shopping delivered straight to their car, no matter where they are.
Volvo’s new digital keys technology will allow consumers to choose their car as a delivery option when ordering goods online.
To view Multimedia News Release, go to http://www.multivu.com/mnr/65010-volvo-pilots-roam-delivery-service
