A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
The Yankee Candle Company, Inc., the world’s largest manufacturer of premium scented candles, today announced the launch of three new fragrances for the holidays. Inspired by nostalgic family recipes, these new holiday scents reflect the traditional colors of the holiday season with a fresh approach: moss green, rich red and icy white. The new holiday fragrances are available for purchase now at Yankee Candle’s more than 550 retail stores, www.yankeecandle.com and select specialty retailers and gift shops.
To view Multimedia News Release, go to http://www.multivu.com/mnr/56812-yankee-candle-new-holiday-scents
The most desirable things in life have a precious, enduring beauty that should be treasured forever. Discover the timeless allure of Vintage by Kate Moss, the stunning new fragrance from the world's most famous supermodel, available from September 2009.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/prne/cotysas/37560/
Director: Mark Lieberman
Executive Producers: Hollis H.D. Stephenson, Coy Harris
Cinematography: Brendan Walsh, Kyle Griffin
Gaffer: Cory Lonas
Best Boy: Perry Kerr
Lead VFX Artist: Mark Lieberman
Animator/Illustrator: Adam Cusack
3D Artist: Anton Moss
Roto Artists: Andrew Dohan, Brendan Walsh
Title Designer: Matthew Robertson
T.I. - Swagger Like Us Lyric:
(M.I.A. Sample) Hook Repeats 2x
no one on the corner have swagger like us
swagger like us, swagger swagger like us
no one on the corner have swagger like us
swagger like us, swagger swagger like us
no one on the corner have swagger like us
swagger like us, swagger swagger like us
no one on the corner have swagger like us
swagger like us, swagger swagger like us
[Kanye West]
Mr. West is in the building
swagger on a hundred thousand, trillion
Ayo I know I got it first
I’m Christopher Columbus, y’all just the pilgrims
Thanksgiving do we even gotta question
Hermes Pastelle I pass the dressing
My attitude is tattooed
that means permanent so I guess i should address it, huh?
My swagger is mick jagger
every time I breathe on the track I asthma attack it
Why he’s so mad for, why he gotta habit
cuz I slaved my whole life, now I’m the master
Na-Na-Na, How it feel to wake up and be the shit and the urine Na-Na-Na-Na-Na
Trying to get that Kobe number, one over Jordan
(M.I.A. Sample)
no one on the corner have swagger like us
swagger like us, swagger swagger like us
no one on the corner have swagger like us
swagger like us, swagger swagger like us
no one on the corner have swagger like us
swagger like us, swagger swagger like us
no one on the corner have swagger like us
swagger like us, swagger swagger like us
[Jay-Z]
cheaaa
No one on the corner gotta bop like this
can’t wear skinny jeans cuz my knots don’t fit
No one on the corner gotta pocket like this
so I rock Roc jeans cuz my knots so thick
You can learn how to dress just by
jocking my fresh
jocking jocking my fresh
jocking jocking my fresh
Follow my steps, it’s the road to success
where the niggas know you thoro
and the girls say yes
But I can’t teach you my swag
you can pay for school but you can’t buy class
School of hard knocks I’m a grad
and that all-blue yankee is my graduation cap,
it’s Hovaaaaa!!!
Dipping different rovers whipping with the soda
Hovaaaaa!!!
Could u even have any doubt after doubt if its over
(M.I.A. Sample)
no one on the corner have swagger like us
swagger like us, swagger swagger like us
no one on the corner have swagger like us
swagger like us, swagger swagger like us
no one on the corner have swagger like us
swagger like us, swagger swagger like us
no one on the corner have swagger like us
swagger like us, swagger swagger like us
[Lil Wayne]
No one on the corner has swagger like moi, Church
but I’m too clean for these boys
I require what I desire I got stripes, A-di-das
Mami scream papi no mas
Run up in your shit just me no moss
Runnin this shit like I got four thighs
none has swagger like this four gods!
When it comes to styles I got several
sharper than a swagger, dagger all metal
And my jew-elz blue and yellow
the type of shit that make em call you Carmelo
Rules as follows stay true to the ghetto
write your name on the bullet make you feel special
Haaa!!!
What the f**k you boys talking about?
I know its us cuz we the only thing you talk about
(M.I.A. Sample)
no one on the corner have swagger like us
swagger like us, swagger swagger like us
(and I’m done)
no one on the corner have swagger like us
swagger like us, swagger swagger like us
(bye!)
no one on the corner have swagger like us
swagger like us, swagger swagger like us
no one on the corner have swagger like us
swagger like us, swagger swagger like us
[T.I.]
yea
ha!
ya think?
thats right
You go see Weezy for the wordplay,
Jeezy for the birdplay,
Kanyeezy for di
THINK: Intense liquid colour plus smooth lacquer shine.
WHAT IT IS: The end of lip colour as you know it. The future is neither lipstick nor gloss — but bigger and better than both. New Rimmel London Show Off Lip Lacquer features a breakthrough lacquer formula packed with pure colour pigments that deliver bold, saturated colour and intense mirror-like shine all in one show-stopping tube. This creamy lip lacquer is smooth, not sticky, for supreme comfort and phenomenal shine that lasts all day.
To view Multimedia News Release, go to http://www.multivu.com/mnr/62859-rimmel-london-show-off-lip-lacquer-kate-moss
THINK: A decade of iconic beauty with Rimmel London and Kate Moss.
WHAT IT IS: Kate Moss’s supermodel style, captured in a bold lipstick collection. In honor of Kate Moss’ ten years as the face of Rimmel London, the brand presents five Lasting Finish Lipsticks created exclusively by Kate Moss. Each lipstick is housed in a chic matte black bullet, reflective of Kate Moss’s signature rocker style, and bears the supermodel’s signature in bold red for elegance with an edge.
To view Multimedia News Release, go to http://www.multivu.com/mnr/53874-rimmel-london-kate-moss-lasting-finish-lipstick-collection
McDonald’s USA today announced the 2012 McDonald’s Inspiration Celebration Gospel Tour, a free summer concert series that featured multi-award winning gospel artist Fred Hammond, raised more than $46,000 this year to support local Ronald McDonald House Charities (RMHC) Chapters and the Charity’s important mission of helping improve the health and well being of children and families.
Currently in its sixth year, McDonald’s pioneered the annual gospel tour as a way to bring positive, uplifting messages and entertainment to communities nationwide and emphasize the importance of giving back. With Hammond as the 2012 headliner, the free, nine-city tour also featured contemporary and urban gospel artists Byron Cage, 21:03, Canton Jones, J Moss, Myron Butler and VaShawn Mitchell, in select cities.
To view Multimedia News Release, go to http://www.multivu.com/mnr/57816-mcdonalds-rmhc-inspiration-celebration-gospel-tour-fred-hammond
marc jacobs beauty announces lila moss as the newest face of the brand for 2019. a dedicated campaign will debut in the uk at harvey nichols, the brand’s new exclusive retail partner in the uk and ireland, on october 11, 2018. this is the first official image of the campaign featuring lila, shot by david sims with creative direction by katie grand, makeup by diane kendal, hair by guido palau and nails by jin soon choi.
“when i met lila grace for the first time in 2008, i was on a holiday in ibiza and went to formentera for the day to visit with her mom, kate moss, and other friends and family. at just 6 years old, lila’s strong character, demeanor and great beauty was already very apparent.
The top model, style icon and fashion designer Kate Moss has visited the Coty factory in Granollers, near Barcelona to see her new fragrance, Vintage Muse, coming off the production line.
Upon her arrival, Kate was greeted by the factory director, Patrick Bourque, who revealed that the factory is producing a staggering 60 bottles of Vintage Muse per minute, around the clock.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/prne/cotybeauty/46304/
http://www.drmartinmoss.com IT-Projekte erfolgreich steuern: Mit IT-Projektsteuerung lernen Sie, wie Sie jedes IT-Projekt auf ein sicheres Fundament zu stellen. Sie erfahren meine in der Praxis erprobten Strategien und Tricks der IT-Projektsteuerung, mit denen ich bereits zum Scheitern verurteilte Projekte zu einem erfolgreichen Ausgang verholfen habe”, erklärt Dr. Moss.