A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
The Yankee Candle Company, Inc., the world’s largest manufacturer of premium scented candles, today announced the launch of two new fragrances and the return of three favorites in its popular limited edition Man Candles collection. Two new fragrances, MMM, Bacon! and Movie Night™, join Man Town™, First Down™ and Riding Mower™. The collection, launched last year to tremendous response, was created uniquely for men to be enjoyed in their “man town,” whether that is the den, the basement or even the garage. These limited edition fragrances will be available for purchase starting in May at more than 557 Yankee Candle retail stores, www.yankeecandle.com and select specialty retailers and gift shops. To celebrate the arrival of the collection, Yankee Candle is simultaneously launching a series of social media contests, offering consumers the chance to win samples of the Man Candles II collection. The brand is also encouraging fans to share their excitement on Facebook and Twitter by using the hashtag #MMMBacon.
To view Multimedia News Release, go to http://www.multivu.com/mnr/61623-yankee-candle-man-candles-ii-collection
Five international apprentices visited global construction and mining equipment manufacturer XCMG's headquarters in Xuzhou, China for a one-week immersive XCMG Apprentice Program from January 18 to 24.
The program was the company's first time bringing global apprentices to China; five apprentices from the United States, Brazil, Russia, Kenya and Pakistan stood out from a global selection.
The participants came from different backgrounds but shared the same interest towards the construction and machinery industry. In addition to the comprehensive tour led by XCMG employees that included visits to the crane assembly factory and Asia's largest vibration and noise lab, as well as engaging activities like operating excavators, the apprentices also acted as their mentors' assistants, learning about the state-of-the-art technologies in construction machineries through a day's work.
"XCMG has a keen focus on cultivating talents and encouraging communication through educational programs like XCMG Apprentice, which has introduced XCMG's technological and innovational achievements to the international community," said Wang Min, chairman and president of XCMG.
To view the multimedia release go to:
http://www.multivu.com/players/uk/7764851-xcmg-apprentice-program/
Wildfires are a serious risk to property and lives in every state in the country. Last year alone the National Interagency Fire Center (NIFC) reported there were 63,212 fires in the U.S. and Puerto Rico that burned 3,595,613 million acres – that’s roughly the size of Connecticut! In an effort to help raise community and homeowner awareness about preparing for wildfires, State Farm and the National Fire Protection Association (NFPA) are working together and encouraging residents to take action during national Wildfire Community preparedness Day.
To view the Multimedia News Release, go to: http://www.multivu.com/players/English/7452831-state-farm-weather-preparedness/
The end of Walmart’s latest Facebook campaign for hunger relief is nearing and the company is encouraging last-minute “likes” that will help determine which of 100 U.S. cities will receive $1.5 million in grants. The “Fighting Hunger Together” Facebook campaign will end at 12 a.m. on Jan. 1 and is part of the company’s $2 billion commitment to help fight hunger through 2015.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/walmart/47721/
The end of Walmart’s latest Facebook campaign for hunger relief is nearing and the company is encouraging last-minute “likes” that will help determine which of 100 U.S. cities will receive $1.5 million in grants. The “Fighting Hunger Together” Facebook campaign will end at 12 a.m. on Jan. 1 and is part of the company’s $2 billion commitment to help fight hunger through 2015.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/walmart/47721/
A new national marketing campaign starring Wallace & Gromit, is setting out to inspire Britons to take a holiday at home this year. Led by VisitEngland and supported by the home nation tourist boards of Scotland, Wales and Northern Ireland, ‘Great Adventure’ is focused on a television advertisement encouraging consumers to book through their local travel agent.
Now, the national tourist board has released some cracking behind the scenes footage with Wallace & Gromit offering a peek at how the ad was made.
To view Multimedia News Release, go to http://www.multivu.com/mnr/61919-visitengland-ad-campaign-wallace-gromit
In response to the devastation wrought by Typhoon Haiyan in the Philippines, the Ad Council joined the Administrator of the U.S. Agency for International Development (USAID), Dr. Rajiv Shah, and the Center for International Disaster Information (CIDI) to launch a series of television, radio, print and Web public service advertisements (PSAs) encouraging Americans to make financial contributions to disaster relief efforts. The PSAs direct audiences to visit PhilippinesRelief.AdCouncil.org, where they can contribute to support the short and long-term recovery operations, providing supplies and services to those affected by the typhoon.
To view the Multimedia News Release, go to http://www.multivu.com/mnr/64502-ad-council-usaid-cidi-encourage-support-typhoon-relief-philippines
The European Head and Neck Society (EHNS) and the Make Sense Campaign, today announced the launch of the Third Annual Head and Neck Cancer Awareness week (21–25 September). Through the pan-European Awareness Week, the EHNS and Make Sense Campaign promote education on head and neck cancer risk factors, disease prevention and disease signs and symptoms for both patients and healthcare professionals.
“Each year 350,000 people are diagnosed with head and neck cancer across Europe, and over half will not be alive after five years. However, if diagnosed and treated earlier, patients can have an 80 – 90% survival rate.” said Professor René Leemans, President of the EHNS and Professor and Chief of Otolaryngology – Head and Neck Surgery at VU University Medical Centre. “Through the Make Sense Campaign we are educating people about the early signs of the disease and encouraging them to seek professional help in a timely manner. Additionally, we are advocating for the best possible standards of patient care so that their outcomes can be optimised once they have been diagnosed with the disease.”
To view the multimedia release go to:
http://www.multivu.com/players/uk/7628151-support-head-neck-cancer-patients/
Following FDA approval of the AspireSR® generator for the VNS Therapy® system in June 2015, more than a thousand patients with drug-resistant epilepsy across the United States have received this new treatment option. Many of these patients are experiencing benefits which have positively impacted their lives – and are sharing their stories during Epilepsy Awareness Month with the hope of encouraging others to seek new treatments for drug-resistant epilepsy. Numerous hospitals nationwide have begun providing the AspireSR device to patients with drug-resistant epilepsy – a condition that affects as many as one-third of people with epilepsy, causing them to have seizures in spite of treatment with antiepileptic medications.
The VNS Therapy system is a minimally invasive option in which a medical device is placed under the skin in the upper chest area during an outpatient procedure. The device sends mild electrical pulses through the vagus nerve to areas of the brain known to be associated with seizures. The new AspireSR generator takes the VNS Therapy technology a step further – detecting relative heart-rate increases that are often associated with seizures in people with epilepsy and providing responsive stimulation in an attempt to stop and shorten seizures and improve recovery.
To view the multimedia release go to:
http://www.multivu.com/players/English/7651751-livanova-aspiresr-treatment/