A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
Aflac, the number one provider of supplemental insurance in the United States, and recognized six times by Ethisphere as one of the World’s Most Ethical Companies, is once again teaming with Macy’s to produce and sell the 2012 Aflac Holiday duck . This is the twelfth year that Aflac and Macy’s are selling the annual plush duck, with all net proceeds going to support research and treatment for childhood cancer.
To view Multimedia News Release, go to http://www.multivu.com/mnr/58454-aflac-macys-annual-holiday-duck-design-pediatric-cancer-patient-atlanta
The St. Baldrick’s Foundation, a volunteer-powered charity dedicated to funding childhood cancer research, announces its Kids Are Special: Let’s Treat Them That Way national campaign. Focused on celebrating kids and giving them the happy childhoods they deserve, the campaign highlights the need for finding treatments that are specifically designed for kids with cancer.
With this bold new initiative, St. Baldrick’s looks to change the narrative around pediatric cancers, by showing kids as their truest selves – fun-loving, carefree, refreshingly honest, and always a little goofy. St. Baldrick’s puts the emphasis back on kids, while disempowering the label of “cancer.” All communication is strategically designed to remind us all that as adults we have the power to give kids happy childhoods free from cancer by helping to fund the best research worldwide. The campaign includes TV, print, radio, digital, and billboard placements featuring real kids doing kid-like things; from playing with their food to getting caught with paint on their faces, all with the message: Kids Are Special: Let’s Treat Them That Way.
To view the multimedia release go to:
http://www.multivu.com/players/English/7610752-st-baldricks-kids-are-special/
This February, the American Academy of Pediatric Dentistry (AAPD) is celebrating National Children’s Dental Health Month by hosting the Tournament of Tooth Care, showcasing how parents and caregivers can help their kids fend off the Mouth Monsters –a.k.a. tooth decay. Parents and caregivers can tune in to the Mouth Madness to learn how to help little teeth take on the Mouth Monsters one big game at a time.
“Tooth decay in children is a major health epidemic for adolescents across the country,” said Dr. Robert Delarosa, AAPD President. “National Children’s Dental Health Month is a great time for parents to keep their children’s dental health top of mind. Make it a priority this month to find a Dental Home – or home base – for your child’s oral health needs and be sure your next check-up is on the calendar.”
Tooth decay is one of the top chronic infectious diseases among children in the U.S. About 60 percent of children will have had tooth decay at some point by age five. More than 50 million school hours are missed every year by school-aged children in the U.S. due to dental visits or problems. And tooth decay isn’t just bad for oral health; children who develop tooth decay at a young age are at a greater risk for developing problems with oral and general health, as well as with educational and social development.
To view the multimedia release go to:
http://www.multivu.com/players/English/7750251-aapd-mouth-madness-dental-health/
Sanofi Pasteur, the vaccines division of Sanofi (EURONEXT: SAN and NYSE: SNY), announced today that its first doses of Fluzone® (Influenza Vaccine) for the 2016-2017 influenza (“flu”) season have been released by the U.S. Food and Drug Administration (FDA) for shipment. This represents the first of more than 65 million total doses of seasonal influenza vaccine manufactured by Sanofi Pasteur that will be delivered to U.S. health care providers and pharmacies beginning in July and continuing throughout the remainder of the year. Sanofi Pasteur plans to increase its supply to respond to the shifting pediatric public health needs.
Seasonal influenza activity typically occurs between October and May and peaks between December and February. However, influenza activity peaked noticeably late last season occurring in early March 2016.1 Influenza seasons are always unpredictable as new influenza strains emerge and strain activity fluctuates throughout the year, making timely vaccination even more important to help protect against the virus, especially for seniors, young children and infants six months of age and older.
To view the multimedia release go to:
http://www.multivu.com/players/English/7842051-sanofi-pasteur-influenza-vaccine/
Miami Children's Health Foundation (MCH Foundation) celebrated its 10th Anniversary Diamond Ball on Oct. 29, raising nearly $1.6 million, benefiting the children and families at Nicklaus Children’s Hospital. More than 800 guests took part in the glamourous affair, which combined couture fashion and costumes inspired by the theme “Into the Woods.”
This year, world-renowned guitarist, singer, and composer José Feliciano was inducted into the Ambassador David M. Walters International Pediatric Hall of Fame. After receiving his award, Mr. Feliciano also entertained the crowd with a live performance. Mr. Feliciano was recognized for his commitment to helping children through the Jose M. and Susan L. Feliciano Charitable Foundation for Children and the Arts and for his achievements in the world of music as the first Latin artist to cross over into the English music market.
To view the multimedia release go to:
http://www.multivu.com/players/English/7969051-miami-childrens-health-foundation-diamond-ball/
St. Jude Children’s Research Hospital is naming the institution’s principal research tower after Donald Pinkel, M.D., whose legacy of driving progress toward advancing cures for pediatric catastrophic diseases continues at the institution today.
When St. Jude was established 55 years ago, Pinkel, the hospital’s first medical director, committed to finding cures for childhood cancer, leading to groundbreaking treatments that saved countless children’s lives. Many of these cancers were deemed incurable prior to Pinkel’s research, but his distinct approach to eradicating diseases established a model for how cancers could be treated.
To view the multimedia release go to:
https://www.multivu.com/players/English/7924752-st-jude-childrens-research-hospital-donald-pinkel-tower/
When a life-changing diagnosis brings moments of uneasiness, a glimmer of hope can make all the difference in bringing solace. As hope comes in many forms, Extended Stay America® hotels, the nation’s largest owner operated hotelier, announced today the launch of the brand’s latest initiative in their continued support for the fight against cancer – the “Give Hope” program. A natural evolution of Extended Stay America’s partnership with the American Cancer Society, the “Give Hope” program provides a platform to raise awareness and funds for pediatric cancer research.
To view the multimedia release go to:
https://www.multivu.com/players/English/8060751-extended-stay-america-give-hope-cancer-research/
GW Pharmaceuticals plc (Nasdaq: GWPH, “GW,” “the Company” or “the Group”), a biopharmaceutical company focused on discovering, developing and commercializing novel therapeutics from its proprietary cannabinoid product platform, along with its U.S. subsidiary Greenwich Biosciences, announced today that The New England Journal of Medicine has published results from a Phase 3 study of Epidiolex® (cannabidiol) in children with Dravet syndrome.1 Epidiolex, GW’s lead product candidate and the potential first in a new category of anti-epileptic drugs, is a liquid formulation of purified, plant-derived cannabidiol (CBD), a non-psychoactive cannabinoid, which is being studied for the treatment of a number of rare, severe pediatric-onset epilepsy disorders. In the study, Epidiolex significantly reduced monthly convulsive seizure frequency compared to placebo in highly treatment-resistant children when added to existing treatment. Treatment with Epidiolex was generally well tolerated, with a safety profile consistent with prior open label experience.
To view the multimedia release go to:
https://www.multivu.com/players/uk/8109951-gw-pharmaceuticals-study-epidiolex/
St. Jude Children’s Research Hospital patients who completed kindergarten during their treatment for pediatric cancers celebrated at a graduation ceremony.
For the 10th straight year, St. Jude honored 14 patients from around the United States who completed kindergarten while battling life-threatening illnesses like leukemia and brain tumors. Dozens of families and St. Jude doctors, nurses, and staff cheered for the young students, who completed kindergarten in the St. Jude School Program by Chili’s.
Each year, the school program commemorates students who have completed kindergarten coursework with a special ceremony. The children present a song for the families and St. Jude staff, receive their diplomas and celebrate the milestone with their fellow students.
To view the multimedia release go to:
https://www.multivu.com/players/English/7924755-st-jude-celebrates-kindergarten-graduation/
Changes in the treatment of pediatric cancer over recent decades have translated to a reduced risk of serious, long-term late health effects of cancer therapy. This is according to the latest analysis from the Childhood Cancer Survivor Study (CCSS), a National Cancer Institute-funded resource for late-effects research, led by investigators at St. Jude Children’s Research Hospital.
“This is the first comprehensive study to demonstrate how changes in treatments over time have impacted the occurrence of late effects experienced by childhood cancer survivors,” said Todd Gibson, Ph.D., assistant member of the Department of Epidemiology and Cancer Control at St. Jude. “We found the 15-year cumulative incidence of people reporting at least one severe health condition decreased from 12.7 percent among childhood cancer survivors diagnosed in the 1970s to 10.1 percent for those diagnosed in the 1980s to 8.8 percent in the 1990s–a statistically significant decline.”
To view the multimedia release go to:
https://www.multivu.com/players/English/7924756-st-jude-childhood-cancer-survivorship-asco-2017/
In an effort to improve outcomes for patients with some of the deadliest childhood cancers, St. Jude Children’s Research Hospital scientists have created the world’s largest collection of pediatric solid tumor samples, drug-sensitivity data and related information and have made the resource available at no charge to the global scientific community.
St. Jude and the Howard Hughes Medical Institute collaborated to create the resource, known as the Childhood Solid Tumor Network. The work is reported today as an advance online publication in the scientific journal Nature.
“Survival rates for children with recurrent solid tumors have not improved significantly in more than 20 years and remain below 30 percent,” said corresponding author Michael Dyer, Ph.D., chair of the St. Jude Department of Developmental Neurobiology and a Howard Hughes Medical Institute investigator. “This research will change that by promoting scientific collaboration to leverage the efforts of researchers worldwide to advance understanding and ultimately treatment of pediatric solid tumors.”
To view the multimedia release go to:
https://www.multivu.com/players/English/8121952-st-jude-childrens-childhood-solid-tumor-network/
