Researchers studying the genetic roots of the most common malignant childhood brain tumor have discovered missteps in three of the four subtypes of the cancer that involve genes already targeted for drug development.
A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
The National Bone Health Alliance (NBHA), a public-private partnership with 42 member organizations, is urging a simple solution to a big problem: if it’s 50+ fracture, request a test. This is the call-to-action for the NBHA’s new public and healthcare professional education campaign – 2Million2Many (www.2Million2Many.org).
The campaign reflects the two million bone breaks that occur in the U.S. each year that are caused by osteoporosis and urges the public and healthcare professionals alike to take action and request a test for osteoporosis when someone age 50 or older breaks a bone. Despite the fact that 50 percent of osteoporosis-related repeat fractures can be prevented with existing treatments, only two in 10 initial bone breaks get a follow-up test or treatment for osteoporosis.
To view Multimedia News Release, go to http://www.multivu.com/mnr/56192-national-bone-health-alliance-nbha-prevent-osteoporosis-2million2many
Amway’s ARTISTRY® brand has licensed a leading anti-aging technology for its anti-wrinkle firming serum, the newest addition to the ARTISTRY intensive skincare line. This serum will be the first and only anti-aging product to utilize a breakthrough patented Targeting Complex technology that reduces the common side effects found in retinol treatments.
Using exclusive patented technology from the University of Michigan, ARTISTRYintensive skincare anti-wrinkle firming serum combats the visible effects of aging by boosting collagen while minimizing the level of sensitivity associated with retinol use.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54642-amway-artistry-intensive-skincare-line-anti-wrinkle-firming-serum
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University Hospitals (UH) Case Medical Center has announced a $250 million initiative that promises to dramatically change how drugs will advance from discovery in the laboratories to commercialization, resulting in greater access to advanced treatments and cures for patients. The first-of-its-kind initiative, named The Harrington Project for Discovery & Development, is powered by a $50 million gift – the largest donation in the health system’s history – from the Harrington family, recognized entrepreneurs and philanthropists in Cleveland.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54909-university-hospitals-uh-harrington-discovery-institute-development-project
Today, Solta Medical, Inc. (Nasdaq: SLTM), the pioneer in fractional resurfacing and non-invasive skin tightening and a global market leader in aesthetic treatments, announced the arrival of its groundbreaking Liposonix technology in the United States and Canada. Using advanced high-intensity focused ultrasound (HIFU) technology, Liposonix is a non-surgical permanent fat reduction procedure that has been clinically shown to slim down the waistline by one pant or dress size without surgery or downtime. It is indicated for non-invasive waist circumference reduction for use on both the abdomen and love handles.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54037-solta-liposonix-custom-contouring-waistline-fat-reduction
Fifty-two year-old Paul McNeel, a fire chief from Leonardtown, Maryland was 37 in 1996 when a sudden health problem caused the loss of his small intestine. Almost all of it had to be surgically removed to save his life. For 13 years after that, McNeel continued to fight fires and stayed alive by feeding himself a special liquid formula through a tube that went from a port in his chest directly to his heart and into his bloodstream. Over time that feeding process called TPN or total parenteral nutrition took a toll on his body; it was damaging his liver and he began to suffer frequent and worsening infections. McNeel needed a life-saving transplant that 13 years earlier would not have been survivable. Thanks to research into improved surgical methods, better anti-rejection medications and a better understanding of the small intestine, McNeel was able to have that transplant in May 2009 at Georgetown University Hospital under the care of Thomas Fishbein, MD, executive director of the Georgetown Transplant Institute and a specialist in small bowel transplants.
To view Multimedia News Release, go to http://www.multivu.com/mnr/52073-small-intestine-transplant-experts-hosted-by-georgetown
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EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, today announced that the company’s state-of-the-art research center in Billerica, MA, is LEED® Gold certified under the U.S. Green Building Council and verified by the Green Building Certification Institute (GBCI). LEED® is the nation’s preeminent program for the design, construction and operation of high performance green buildings. The Billerica research facility supports the company’s commitment to developing and discovering innovative treatments in oncology, neurodegenerative diseases and fertility, and is one of only five laboratories in Massachusetts to achieve this high rating.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/emdserono/49715/
Instant improvements and no recovery time make the new ARTISTRY® intensive skincare renewing peel a convenient, at-home alternative to acid-based peels. It provides a gentle, one-step option that’s cost-effective and rivals benefits experienced from professional treatments.
Intensive skincare renewing peel is appropriate for women of all skin types, including Miss America 2011 Teresa Scanlan. With traveling 20,000 miles a month, Scanlan simply doesn’t have time to regularly visit a dermatologist or wait for recovery from redness experienced after professional treatments. “I’ve turned to at-home alternatives. I love ARTISTRY intensive skincare renewing peel, which provides my skin with what I need in just minutes, without worrying about irritation,” comments Scanlan.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/artistrybeauty/48331/
