A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
This London 2012 Olympics video, was created as a motivational piece also for the legacy of London 2012. Look at what is being said and ask yourself, are you going for what you want in your life, or are you busy watching other people and staying stagnant. This video was made at a point where it was hard to feel like a WINNER, but there is nothing more powerful than being able to express yourself through creativity. Go for your dreams, never stop. Chiller Scheme's And The Winner is... Video Presentation outlines what is needed to be a Winner (link here) - http://www.youtube.com/playlist?list=PL11195D972F3CE84E Follow Chiller Scheme's Twitter here :- Chiller Scheme Twitter - http://www.twitter.com/mrscheme
Bank of the West has seen a rise in mortgage loan applications since April as homeowners seek to take advantage of low interest rates under the government’s Home Affordable Refinance Program (HARP) 2.0.
For consumers wanting to learn more about HARP, Bank of the West has published Eight Essential Harp Tips and introduced an educational video series on HARP loans that can be viewed on YouTube at YouTube.com/Bankofthewest.
“We are anticipating that one out of every five new borrowers will be a homeowner seeking a HARP 2.0 refinance loan this year,” said Karen Mayfield, Bank of the West’s National Sales Manager for the Mortgage Banking Division. “This program is providing real relief for homeowners who are current on their mortgage but have been unable to refinance due to a decline in the value of their home.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/54577-bank-of-the-west-mortgage-loan-applications-refinance-harp-2-0
In the 2011/2012 vacation season, Riu Hotels & Resorts will open four new hotels in Mexico, Caribbean and Costa Rica and overhaul four more. Riu Hotels & Resorts is one of Apple Vacations’ most popular hotel chains. In 2011, 10 Riu Hotels in Mexico, the Caribbean and Costa Rica were awarded the Golden Apple Award for exceptional service, quality and value, as rated by Apple Vacations’ customers.
“Apple Vacations has had a long and successful partnership with Riu Hotels,” said Sandy Babin, Apple Vacations’ Vice President of Marketing. “Since 1998, Apple Vacationers have enjoyed Riu Resorts, referred their friends and returned time and again to experience Riu’s exceptional service and consistency.”
To view Multimedia News Release, go to http://www.multivu.com/players/English/55585-apple-vacations-riu-hotels-and-resorts
Sixty percent of young adult drivers (16-24) said they have texted while driving, according to a national survey released by the Ad Council. To educate young adult drivers about the dangers of texting while driving, the National Highway Traffic Safety Administration (NHTSA), the State Attorneys General and Consumer Protection Agencies, and the Ad Council today revealed new public service advertisements (PSAs) featuring NASCAR driver Kasey Kahne®. The new PSAs are being unveiled today to coincide with the first nationwide Stop the Texts Day, and the start of National Youth Traffic Safety Month.
To view Multimedia News Release, go to http://www.multivu.com/mnr/55966-NASCAR-driver-Kasey-Kahne-and-the-Ad-Council-prevent-texting-and-driving
Helzberg Diamonds is proud to announce a partnership with leading jockey, Javier Castellano, rider of Gemologist in the 2012 Kentucky Derby on May 5, 2012. Castellano will drive awareness for Helzberg’s featured products in advance of the 138th Run for the Roses.
“Our customers consider us their gemologist, so it was a natural fit since Javier is riding Gemologist in the 2012 Kentucky Derby,” said Beryl Raff, chairman and CEO of Helzberg Diamonds. “We are thrilled to partner with Javier, who is an incredible athlete and a true success story. He has worked his way to the pinnacle of racing success after years of dedication and hard work.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/56000-helzberg-diamonds-jockey-javier-castellano-on-gemologist-kentucky-derby
Mr. Freeze: Reverse Blast was introduced at Six Flags St. Louis today with St. Louis Cardinal and World Series MVP David Freese on-hand for the first official ride. Eighteen members of Big Brothers Big Sisters of St. Louis joined Freese for the inaugural launch-ride on the park’s newest twist to one of its most popular thrill rides. Mr. Freeze: Reverse Blast sends riders backwards through a 190-foot tunnel, into a 180-degree inversion, then climbs more than 200-feet in the air where they will find themselves suspended, dangling in the air, before repeating the entire chilling experience.
“I have been coming to Six Flags since I was a kid and the roller coasters have always been my favorite,” said Freese. “I was really excited to ride Mr. Freeze: Reverse Blast. The backwards launch and experience of going up the tower facing straight down is a real rush.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/55951-mr-freeze-reverse-blast-launches-at-six-flags-st-louis
Brand USA, the new tourism marketing entity responsible for promoting the United States to world visitors, unveiled the USA’s first-ever comprehensive marketing campaign today during a press conference at International Pow Wow, the largest U.S. travel trade show held this week in Los Angeles. The campaign showcases the diversity of experiences available in the United States in a fresh and unexpected light, inviting visitors to “Discover this land, like never before.”
“Our goal is nothing short of rekindling the world’s love affair with the USA – the place, the spirit and the dream,” said Brand USA CEO Jim Evans. “We want to spread America’s message of welcome around the world and invite travelers to experience the limitless possibilities the United States has to offer. So we asked ourselves, ‘how can we best speak to multiple countries, across countless languages and cultures?’ We found the answer lay in the only truly universal language—music.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/55891-usa-international-travel-campaign-discover-this-land-like-never-before
As Britain prepares for a summer of sport, Steve Backley, former javelin world record holder and Olympian turned business motivator and author, calls on British businesses to encourage competition, following two polls showing many embrace competition at work.
The first report, carried out by The National Business Awards in partnership with Orange, shows that 65% of workers agree winning is important to them, with over two thirds believing healthy competition brings out the best in people and almost 40% acknowledging they enjoy a competitive environment at work. However, many employees say competitiveness is not encouraged in their workplace enough.
Over 40% say being rewarded for their achievements at work encourages them to ‘up their game’, yet nearly 60% said they are not praised enough by bosses when they do well at work. Over half of the workers canvassed also said they would like to feel part of a winning business and would be proud if their place of work was recognised by winning an external award.
To view Multimedia News Release, go to http://www.multivu.com/mnr/53807-national-business-awards
Today, Race Imboden, 2011 graduate of The Dwight School, was officially named to the United States Olympic Team by the US Fencing Association. After the fourth World Cup event, he mathematically qualified for the Olympics in Men’s Foil based on his high team rankings. Mr. Imboden is currently #6 in the FIE (Fédération Internationale d’Escrime) World Senior Rankings, #2 in the USA Fencing Division I (Senior), and #2 in the USA Fencing Under 19 Division (Junior).
“I couldn’t be more excited and honored to be competing as a member of Team USA, especially in London because my mother’s home country is England. For nine years, I have been working toward this goal with the amazing support and sacrifice of my parents to whom I’m eternally grateful. I’m also grateful to The Dwight School, which helped me to achieve my dream of competing in the Olympics by allowing me the time and flexibility to train, travel the world, and compete while I was a student,” said Mr. Imboden.
To view Multimedia News Release, go to http://www.multivu.com/mnr/55749-race-imboden-dwight-school-alumnus-united-states-olympic-fencing-team
Want to keep employees satisfied in their jobs without one foot out the door? Give them a little credit, a new OfficeTeam survey suggests. Nearly half (49 percent) of workers interviewed said they would be somewhat or very likely to leave their current position if they didn’t feel appreciated by their manager.
To view Multimedia News Release http://www.multivu.com/mnr/55074-officeteam-survey-video-bloopers-employee-recognition-ideas