Sanofi (EURONEXT: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that data from two Phase 2 trials with SAR236553/REGN727, an investigational, high-affinity, subcutaneously administered, fully-human antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9), were presented at the American College of Cardiology’s (ACC) 61st Annual Scientific Meeting in Chicago.
The data showed that treatment with SAR236553/REGN727 over 8 to 12 weeks significantly reduced mean low-density lipoprotein-cholesterol (LDL-C, or “bad” cholesterol) by 40% to 72% in patients with elevated LDL-C on stable dose of statins.
To view Multimedia News Release, go to http://www.multivu.com/mnr/55299-sanofi-regeneron-pharmaceuticals-lipid-lowering-medications-pcsk9-antibody
Sandy's Trauma and Beginning of Grief
Every One of us go Through Grief
OK, so I was on this journey – you can imagine. I loved the journey. And then, the next thing that happened was that tragedy in my life whereby my 3 daughters and their friend were murdered. I want to tell you about my journey of grief during this time. There may be some things there that can help. There are certainly some positive aspects that come out of it, so I’ll tell you about my journey of grief … and you know what? Every one of us here are going to have to go through grief.
Learning Through Adversity
Maybe many of us have already been through grief, and there’s going to be more. We’re all going to go through some adversity at some time. The key thing out of adversity and out of trauma is learning. What is there that you can learn from this event, because you know, those learning experiences are experiences for our soul and it’s the soul that needs the experience.
I’m so Glad I Spoke to my Girls That Night
So, Jenny and Kirsty, they were twins at 19 and Lexie, she was 16 – the next day. And the date was 23rd January 1987. They were living with their mum in the northern Sydney suburb of Pymble and a friend of theirs, Lisa was there as well, so there were 4 of them in the house. I was living about 5 kilometres away in Lindfield, married to Sandra and at that time we had a little 5 year old girl, Lara and a little 3 year old boy, Ian. At about 7 o’clock that Friday night I rang and spoke to Lexie and also spoke to Jenny and Kirsty and I tell you, the mirth and joy in that household was fantastic. They were all preparing to go camping for the Australia Day long weekend. And we taught them about camping, so I was really pleased about that. They were going to be joined by a group of friends to go camping. In retrospect I am so glad I was able to speak to the girls at that time, because at 10 past 9 that night Richard Madrell arrived at the door and professed his love for Jenny who of course had not had anything to do with him for 12 months and all of them wanted to keep him away with their mother even trying unsuccessful to take out an AVO on him. But he arrived at the door and shot her. He then shot Kirsty, then Lisa and then shot Lexie. All over in ten minutes.
My First Reaction
The police hammered on my door at about 2 o’clock in the morning and told me what had happened. My first reaction was that this was impossible … I mean I had only spoken to them several hours earlier. For me it was complete disbelief and I questioned about being shot with a shotgun as I knew something about guns from the army. I questioned the fact that it must have been impossible because with a shotgun you have to load it, fire and then re-load it, re-load it again …. Surely one or two of them are going to be able to get away. Surely not all 4 of them, not all 3 of my girls.
I Still Couldn’t Believe it.
On the way to their home in the police car I was still arguing with the police and I was asking if they had seen their bodies. “Oh, so you haven’t seen their bodies … you haven’t actually been there …. You’ve only been told about this over the radio … so you don’t really know this for sure.” Always thinking and hoping that it’s not true.
My Denial Phase
And then a little bit of doubt would come in and it would be like this: “God, how could you let this happen. No, no no, you haven’t let it happen. But …. If you have … what have the girls done? What have they done to deserve this for goodness sake? There is no God.” And so that’s where my denial phase started.
By Sandy MacGregor – http://www.selfimprovementdeals.com
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In Ellen Hopkins’s Perfect, the riveting companion to Impulse, four teens pursue their goals of perfection which are as different as the paths they take to get there. Everyone wants to be perfect. But what does that really mean? Only you can decide for you, what is perfect. Learn more about this book here, http://bit.ly/ruGJyX and here, TEEN.SimonandSchuster.com and its author here, http://www.ellenhopkins.com/ YA
In their ongoing commitment to support fearless women, Secret Deodorant has created the Mean Stinks program; a supportive Facebook community that gives young women the courage to stand up to a stinky behavior – bullying. To help this cause, Secret is partnering with relatable role models—Amber Riley, best known as Mercedes on the hit FOX show Glee, and Rachel Simmons, nationally renowned relationship expert—to start a movement of “nice.” Together they are giving young women the strength to face challenges associated with bullying and mean behavior. Secret is also partnering with PACER’s National Bullying Prevention Center by donating a portion of proceeds from select Secret Clinical Strength purchases to it’s prevention efforts.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/meanstinks/50863/
The season’s picnics and back-yard barbecues can make it hard to eat right, but a healthy summer lifestyle doesn’t have to mean nibbling on bland fare. With strategic substitutions and smart snacking tips, you can still enjoy a helping of potato salad or a few campfire s’mores without compromising your nutritional goals.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/weightwatchers/50076/
For the second straight year, State Farm and Major League Baseball (MLB) are giving fans from coast to coast the chance to deliver a big hit for their favorite charitable organization. Through the Go To Bat program, an online, charitable initiative driven by State Farm’s commitment to helping communities get to a better state, fans can support the causes that mean the most to them and take their shot at winning one of the $18,000 weekly donations for their favorite charity and a trip for two to the 2011 World Series.
To view Multimedia News Release, go to http://www.multivu.com/mnr/51025-state-farm-go-to-bat
Procter & Gamble’s (NYSE: PG) Vicks DayQuil and Vicks NyQuil have kicked off its “Search for the Most Dedicated NFL Fan” – a new Facebook contest that will reward the NFL’s most dedicated football fan with two tickets to Super Bowl XLV. What does it mean to be Vicks’ dedicated fans? Vicks is searching for a fan that doesn’t miss a moment of the NFL season, despite long distances, no tickets, rain, sleet or snow, cold, cough or flu. A fan that cheers for their team, no matter what – that’s a dedicated fan!
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/vicks/47097/
http://magicofmakingup.us/relationship-break-up-advice-2/
Points You Should know about breaking up.
At the beginning of the romantic relationship, every thing is stunning. You are passionate and in adore. Then right after a whilst every thing begins to fade aside. Your partner generally drift farther aside from you. A single day you know that your few perhaps at a stage of no return and practically nothing you need to do, seems to work.
There is nothing to despairing about, just calm down. You have the energy to change points, and get your few back. But, some perform have to be carried out. Very first you have to keep in mind individuals days when your mate stated all the good things about you and what he liked or dislike about you. Individuals points had been said spontaneously and are precious information about you. You can consider this for your advantage. Try to think of what was stated on the time and see if they make senses.
You may need to consider modifying some things about you that could necessarily mean a lot for your ex or the people around you. You have to believe positive, after a while, you