A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
A growing number of U.S. consumers are taking to their kitchens to cook more frequently, and trying new and more nutritious foods, in an effort to reduce food bills and perhaps their waistlines. These findings are among the results of a recent DuPont™ Teflon® brand Be Cook Aware consumer survey, conducted to understand how the past year’s trends have impacted America’s cooking and eating behaviors at home.
To view Multimedia News Release, go to http://www.multivu.com/mnr/55967-dupont-teflon-be-cook-aware-national-survey
Today UBM plc and partners announce the inaugural Business4Better (B4B) Conference and Exhibition, bringing businesses and nonprofits together to create more vibrant communities and better business results.
The two-day, non-commercial Conference and Exhibition, organized by UBM and producing partners the City of Anaheim together with the Anaheim Convention Center and the Anaheim Orange County Visitor and Convention Bureau, and Freeman, will be held May 1 and 2, 2013 at the Anaheim Convention Center. For more information, visit www.business4better.org.
To view Multimedia News Release, go to http://www.multivu.com/players/English/55937-business4better-ubm/
workerly.com: the Social Network for Freelancers. worker.ly is aimed at providing professionals with the easiest way to get in touch with capable freelancers all over the world. As opposed to many social networks, worker.ly does not focus on personal branding, but only on results. How do we make it happen? Projects are made of real people. The projects you have contributed to probably included more than one person. The good news is: when adding projects to your portfolio, you will be able to add a list of your coworkers. The better news is: adding them will trigger a verification system allowing them to rate your work, confirm that yes, you are a real person and yes, so are they. The long term effect? A network exclusively made of real people!
workerly.com: the Social Network for Freelancers. worker.ly
is aimed at providing professionals with the easiest way to get in
touch with capable freelancers all over the world. As opposed to many
social networks, worker.ly does not focus on personal branding, but
only on results. How do we make it happen? Projects are made of real people. The
projects you have contributed to probably included more than one
person. The good news is: when adding projects to your portfolio, you
will be able to add a list of your coworkers. The better news is:
adding them will trigger a verification system allowing them to rate
your work, confirm that yes, you are a real person and yes, so are
they. The long term effect? A network exclusively made of real people!
workerly.com: the Social Network for Freelancers. worker.ly
is aimed at providing professionals with the easiest way to get in
touch with capable freelancers all over the world. As opposed to many
social networks, worker.ly does not focus on personal branding, but
only on results. How do we make it happen? Projects are made of real people. The
projects you have contributed to probably included more than one
person. The good news is: when adding projects to your portfolio, you
will be able to add a list of your coworkers. The better news is:
adding them will trigger a verification system allowing them to rate
your work, confirm that yes, you are a real person and yes, so are
they. The long term effect? A network exclusively made of real people!
workerly.com: the Social Network for Freelancers. worker.ly is aimed at providing professionals with the easiest way to get in touch with capable freelancers all over the world. As opposed to many social networks, worker.ly does not focus on personal branding, but only on results. How do we make it happen? Projects are made of real people. The projects you have contributed to probably included more than one person. The good news is: when adding projects to your portfolio, you will be able to add a list of your coworkers. The better news is: adding them will trigger a verification system allowing them to rate your work, confirm that yes, you are a real person and yes, so are they. The long term effect? A network exclusively made of real people!
workerly.com: the Social Network for Freelancers. worker.ly
is aimed at providing professionals with the easiest way to get in
touch with capable freelancers all over the world. As opposed to many
social networks, worker.ly does not focus on personal branding, but
only on results. How do we make it happen? Projects are made of real people. The
projects you have contributed to probably included more than one
person. The good news is: when adding projects to your portfolio, you
will be able to add a list of your coworkers. The better news is:
adding them will trigger a verification system allowing them to rate
your work, confirm that yes, you are a real person and yes, so are
they. The long term effect? A network exclusively made of real people!
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http://fitnessweightlosscenter.com - One Arm Dumbbell Tricep Extensions | Tricep Exercises - Another fantastic workout for your ticeps. So many people tend to focus on their biceps but the triceps makes up over 50% of your arm and building them up is a great way to look good at the beach.
Using free weights vs weight machines always carry more risks so it's important to always begin with a lighter weight and work you way up. This will reduce the risk of injury because you will know your limits and not select a higher weight from the start.
For maximum results make sure to extend your arm fully - do not cut the movement short. And as with all weight training exercises slow and steady movements will allow you to work all of the targeted muscles to their fullest. Resist the temptation to move up in weight until you can perform the exercise with the proper technique.
For more info drop by our YouTube channel http://www.youtube.com/user/FitnessWeightLossCtr or visit us on the web at
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http://fitnessweightlosscenter.com - Stiff Leg Deadlifts | Leg Workouts - The is a super exercise for your hamstrings and lower back. As with all weight training exercise proper form/technique is essential for not only getting the most out of the exercise but also to avoid injury. As you lower the bar towards the floor make sure to keep your eyes/head up as this will
facilitate keeping your back straight. And as shown in the video do not bend you knees - remember you are targeting your hamstrings and lower back.
Because technique/form is so essential to the stiff leg deadlifts start off with a lower weight and concentrate on performing the exercise correctly. Do not sway as you lower the weight but try to keep slightly more than 50% of your weight on your heals. And as with all weight training exercises keep your movements slow and steady - again concentrate on form not reps. You will get more out of the exercise with proper form and fewer reps than more reps with incorrect form.
After you have performed the stiff leg deadlift with the correct technique successfully you can increase the weight. Don't make too large a jump in weight but move the weight up slowly. You should not be in a rush to max out the weight. I'll say it again proper form with fewer reps will yield greater results that incorrect form and more reps.
A word of caution - do not perform the stiff legged deadlift if you have lower back problems or are dealing with a lower back injury. And as with any weight training exercise if you begin to experience pain you should discontinue the exercise.
For more info drop by our YouTube channel http://www.youtube.com/user/FitnessWeightLossCtr or visit us on the web at
http://fitnessweightlosscenter.com and find us on Facebook at http://facebook.com/fitnessweightlosscenter
http://fitnessweightlosscenter.com - Standing Barbell Curls - Biceps Workout - A fantastic exercise for isolating the biceps muscles. Everyone wants to show off their guns and the standing barbell curl is a great way to pump up your biceps. As with all exercises to get the maximum results you need to perform the exercise correctly.
The single biggest mistake people make when performing the standing barbell curl is swinging the body back. This defeats the whole purpose of the exercise which is to isolate the biceps muscle. Your body should remain fixed and only the biceps muscles used to lift the weight. If you can't lift the weight without swinging your body back then you need to use less weight until you can effectively perform the exercise.
Another mistake people make is not keeping your elbows tucked into your sides. You should not let your elbows leave your side. Again, we are going for the isolation of the biceps and you do not want to use any other muscles or movements to lift the weight.
The third most common mistake when performing the standing barbell curl is to drop the weight too quickly. To maximize the effectiveness of the exercise you need to slowly lower the weight back to the starting position. If you can't lower the weight slowly you need to reduce the weight until you can. By isolating the biceps on the way up and on the way down you will get amazing results with the standing barbell curl.
For more info drop by our YouTube channel http://www.youtube.com/user/FitnessWeightLossCtr or visit us on the web at
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